Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Transmembrane protein 59-like (TMEM59L) Standard Curve.)
Human Transmembrane Protein 59-Like (TMEM59L) ELISA Kit | TMEM59L elisa kit
Human Transmembrane Protein 59-Like (TMEM59L) ELISA Kit
Gene Names
TMEM59L; BSMAP; C19orf4
Reactivity
Human
Synonyms
Transmembrane Protein 59-Like (TMEM59L); Human Transmembrane Protein 59-Like (TMEM59L) ELISA Kit; TMEM59L; BSMAP; C19orf4; brain-specific membrane-anchored protein; TMEM59L elisa kit
Reactivity
Human
Specificity
Human Transmembrane protein 59-like (TMEM59L) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMEM59L. No significant cross-reactivity or interference between Human TMEM59L and analogues was observed.
Sequence Length
342
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Transmembrane protein 59-like (TMEM59L) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Transmembrane protein 59-like (TMEM59L) Standard Curve.)
Related Product Information for TMEM59L elisa kit
Description: This Human Transmembrane protein 59-like (TMEM59L) ELISA Kit employs a two-site sandwich ELISA to quantitate TMEM59L in samples. An antibody specific for TMEM59L has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TMEM59L present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TMEM59L is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TMEM59L bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12. BSMAP encoding the full-length open reading frame. Northern blot analysis revealed that BSMAP mRNA is preferentially expressed at a high level in the brain. BSMAP has a putative transmembrane domain and is predicted to be a type-I membrane glycoprotein. Genomic sequence analysis revealed that the gene encoding BSMAP consists of eight exons spanning approximately 8 kb and lies 6 kb away from the gene encoding CLF-1 in a reverse orientation. Although no candidate genetic disorders were found to map either to this precise region of chromosome 19 or to the syntenic region of the mouse genome, the highly specific expression of BSMAP mRNA suggests a role for the protein in CNS function.
Background: BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12. BSMAP encoding the full-length open reading frame. Northern blot analysis revealed that BSMAP mRNA is preferentially expressed at a high level in the brain. BSMAP has a putative transmembrane domain and is predicted to be a type-I membrane glycoprotein. Genomic sequence analysis revealed that the gene encoding BSMAP consists of eight exons spanning approximately 8 kb and lies 6 kb away from the gene encoding CLF-1 in a reverse orientation. Although no candidate genetic disorders were found to map either to this precise region of chromosome 19 or to the syntenic region of the mouse genome, the highly specific expression of BSMAP mRNA suggests a role for the protein in CNS function.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
transmembrane protein 59-like
NCBI Official Synonym Full Names
transmembrane protein 59 like
NCBI Official Symbol
TMEM59L
NCBI Official Synonym Symbols
BSMAP; C19orf4
NCBI Protein Information
transmembrane protein 59-like
UniProt Protein Name
Transmembrane protein 59-like
Protein Family
UniProt Gene Name
TMEM59L
UniProt Synonym Gene Names
BSMAP; C19orf4
UniProt Entry Name
TM59L_HUMAN
NCBI Description
This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008]
Uniprot Description
TMEM59L: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. Belongs to the TMEM59 family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p12
Cellular Component: Golgi membrane; membrane; integral to membrane
Similar Products
Product Notes
The Human TMEM59L tmem59l (Catalog #AAA9713941) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9713941 ELISA Kit recognizes Human TMEM59L. It is sometimes possible for the material contained within the vial of "Transmembrane Protein 59-Like (TMEM59L), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
