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Immunohistochemistry (IHC) (Anti-TMEM59L antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit TMEM59L Polyclonal Antibody | anti-TMEM59L antibody

Anti-TMEM59L Antibody (C-Terminus) IHC-plus

Gene Names
TMEM59L; BSMAP; C19orf4
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
TMEM59L; Polyclonal Antibody; Anti-TMEM59L Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal to Human TMEM59L; Human TMEM59L; C19orf4; Transmembrane protein 59-like; BSMAP; anti-TMEM59L antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
Human TMEM59L / C19orf4. Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
342
Applicable Applications for anti-TMEM59L antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
IF (20 ug/ml)
IHC-P (5 ug/ml)
WB (1 ug/ml)
Immunogen
TMEM59L antibody was raised against a 19 amino acid peptide near carboxy terminus of human TMEM59L
Immunogen Description
A 19 amino acid peptide near carboxy terminus of human TMEM59L
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Preparation and Storage
Short term 4 degree C
Long term aliquot and store at -20 degree C
Avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-TMEM59L antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-TMEM59L antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of TMEM59L in mouse brain tissue with TMEM59L antibody at 20 µg/mL.)

Immunofluorescence (IF) (Immunofluorescence of TMEM59L in mouse brain tissue with TMEM59L antibody at 20 µg/mL.)

Western Blot (WB)

(Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/ml.)

Western Blot (WB) (Western blot analysis of TMEM59L in rat heart tissue lysate with TMEM59L antibody at 1 ug/ml.)
Related Product Information for anti-TMEM59L antibody
TMEM59L Antibody, C19orf4 Antibody, Transmembrane protein 59-like Antibody, BSMAP Antibody Description: Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,619 Da
NCBI Official Full Name
transmembrane protein 59-like
NCBI Official Synonym Full Names
transmembrane protein 59 like
NCBI Official Symbol
TMEM59L
NCBI Official Synonym Symbols
BSMAP; C19orf4
NCBI Protein Information
transmembrane protein 59-like
UniProt Protein Name
Transmembrane protein 59-like
Protein Family
UniProt Gene Name
TMEM59L
UniProt Synonym Gene Names
BSMAP; C19orf4
UniProt Entry Name
TM59L_HUMAN

NCBI Description

This gene encodes a predicted type-I membrane glycoprotein. The encoded protein may play a role in functioning of the central nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

TMEM59L: Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. Belongs to the TMEM59 family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 19p12

Cellular Component: Golgi membrane; integral to membrane; membrane

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Product Notes

The TMEM59L tmem59l (Catalog #AAA2400056) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TMEM59L Antibody (C-Terminus) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM59L can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). IF (20 ug/ml) IHC-P (5 ug/ml) WB (1 ug/ml). Researchers should empirically determine the suitability of the TMEM59L tmem59l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM59L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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