Hyaluronan-mediated motility receptor (Hmmr) Recombinant Protein | Hmmr recombinant protein
Recombinant Rat Hyaluronan-mediated motility receptor (Hmmr)
Gene Names
Hmmr; RHAMM
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Hyaluronan-mediated motility receptor (Hmmr); Recombinant Rat Hyaluronan-mediated motility receptor (Hmmr); Hmmr recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-498, Full length protein
Sequence
MGGGVSYVGWLEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEDLKEKDREILCLKQSLEEKVSFSKQIEDLTVKCQLLEAERDDLVSKDRERAESLSAEMQVLTEKLLLERQEYEKLQQNELQSQSLLQQEKELSAHLQQQLCSFQEEMTSERNVFKEQLKLALDELDAVQQKEEQSEKLVKQLEEETKSTAEQLRRLDDLLREKEIELEKRTAAHAQATVIAQEKYSDTAQTLRDVTAQLESYKSSTLKEIEDLKLENLTLQEKVAMAEKRVEDVQQQILTAESTNQEYAKVVQDLQNSSTLKEAEIKEITSSYLEKITDLQNQLRQQNEDFRKQLEEEGAKMTEKETAVTELTMEINKWRLLYEELYDKTKPFQQQLDAFEAEKQALLNEHGATQEQLSKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRSQLAKRKQNELRLQGELDKALGIRHFDPPKAFCHESKENVTLKTPLKEGNPNCC
Sequence Length
498
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Hmmr recombinant protein
This protein is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
57,858 Da
NCBI Official Full Name
Hyaluronan-mediated motility receptor
NCBI Official Synonym Full Names
hyaluronan-mediated motility receptor
NCBI Official Symbol
Hmmr
NCBI Official Synonym Symbols
RHAMM
NCBI Protein Information
hyaluronan-mediated motility receptor
UniProt Protein Name
Hyaluronan-mediated motility receptor
Protein Family
UniProt Gene Name
Hmmr
UniProt Synonym Gene Names
Ihabp; Rhamm
NCBI Description
binds hyaluronan; may play a role in ceell signaling and regulation of the cytoskeleton in the central nervous system [RGD, Feb 2006]
Uniprot Description
Receptor for hyaluronic acid (HA) (). Involved in cell motility (). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity (). May act as a regulator of adipogenisis ().
Research Articles on Hmmr
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Product Notes
The Hmmr hmmr (Catalog #AAA968173) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-498, Full length protein. The amino acid sequence is listed below: MGGGVSYVGW LEKSETEKLL EYIEEISCAS DQVEKYKLDI AQLEEDLKEK DREILCLKQS LEEKVSFSKQ IEDLTVKCQL LEAERDDLVS KDRERAESLS AEMQVLTEKL LLERQEYEKL QQNELQSQSL LQQEKELSAH LQQQLCSFQE EMTSERNVFK EQLKLALDEL DAVQQKEEQS EKLVKQLEEE TKSTAEQLRR LDDLLREKEI ELEKRTAAHA QATVIAQEKY SDTAQTLRDV TAQLESYKSS TLKEIEDLKL ENLTLQEKVA MAEKRVEDVQ QQILTAESTN QEYAKVVQDL QNSSTLKEAE IKEITSSYLE KITDLQNQLR QQNEDFRKQL EEEGAKMTEK ETAVTELTME INKWRLLYEE LYDKTKPFQQ QLDAFEAEKQ ALLNEHGATQ EQLSKIRDSY AQLLGHQNLK QKIKHVVKLK DENSQLKSEV SKLRSQLAKR KQNELRLQGE LDKALGIRHF DPPKAFCHES KENVTLKTPL KEGNPNCC. It is sometimes possible for the material contained within the vial of "Hyaluronan-mediated motility receptor (Hmmr), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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