Gamma-glutamyltransferase 5 (GGT5) Recombinant Protein | GGT5 recombinant protein
Recombinant Human Gamma-glutamyltransferase 5 (GGT5)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
GGT5: Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). Belongs to the gamma-glutamyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Other Amino Acids Metabolism - glutathione; EC 3.4.19.14; EC 2.3.2.2; EC 3.4.19.13; Transferase; Other Amino Acids Metabolism - taurine and hypotaurine; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; Other Amino Acids Metabolism - selenoamino acid; Membrane protein, integral
Chromosomal Location of Human Ortholog: 22q11.23
Cellular Component: anchored to external side of plasma membrane; integral to membrane; plasma membrane
Molecular Function: gamma-glutamyltransferase activity
Biological Process: amino acid metabolic process; leukotriene biosynthetic process; glutathione metabolic process; glutathione biosynthetic process; arachidonic acid metabolic process; leukotriene metabolic process; inflammatory response; proteolysis
Research Articles on GGT5
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Product Notes
The GGT5 ggt5 (Catalog #AAA967509) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-387. The amino acid sequence is listed below: MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL IRQQIDGRGD HQLSHYSLAE AWGHGTG. It is sometimes possible for the material contained within the vial of "Gamma-glutamyltransferase 5 (GGT5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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