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Gamma-glutamyltransferase 5 (GGT5) Recombinant Protein | GGT5 recombinant protein

Recombinant Human Gamma-glutamyltransferase 5 (GGT5)

Gene Names
GGT5; GGTLA1; GGT-REL
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Gamma-glutamyltransferase 5 (GGT5); Recombinant Human Gamma-glutamyltransferase 5 (GGT5); Gamma-glutamyltransferase 5; GGT 5; EC=2.3.2.2; Gamma-glutamyl transpeptidase-related enzyme; GGT-rel; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; Glutathione hydrolase 5; EC=3.4.19.13Cleaved into the following 2 chains:; 1.; GGT5 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-387
Sequence
MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL IRQQIDGRGD HQLSHYSLAE AWGHGTG
Sequence Length
387
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for GGT5 recombinant protein
GGT5; GGTLA1

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,332 Da
NCBI Official Full Name
gamma-glutamyltransferase 5 isoform a
NCBI Official Synonym Full Names
gamma-glutamyltransferase 5
NCBI Official Symbol
GGT5
NCBI Official Synonym Symbols
GGTLA1; GGT-REL
NCBI Protein Information
gamma-glutamyltransferase 5; GGT 5; glutathione hydrolase 5; leukotriene-C4 hydrolase; gamma-glutamyl cleaving enzyme; gamma-glutamyltranspeptidase 5; gamma-glutamyltransferase-like activity 1; gamma-glutamyl transpeptidase-related enzyme; gamma-glutamyl transpeptidase-related protein
UniProt Protein Name
Gamma-glutamyltransferase 5
Protein Family
UniProt Gene Name
GGT5
UniProt Synonym Gene Names
GGTLA1; GGT 5; GGT-rel
UniProt Entry Name
GGT5_HUMAN

NCBI Description

This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GGT5: Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). Belongs to the gamma-glutamyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Other Amino Acids Metabolism - glutathione; EC 3.4.19.14; EC 2.3.2.2; EC 3.4.19.13; Transferase; Other Amino Acids Metabolism - taurine and hypotaurine; Other Amino Acids Metabolism - cyanoamino acid; Lipid Metabolism - arachidonic acid; Other Amino Acids Metabolism - selenoamino acid; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q11.23

Cellular Component: anchored to external side of plasma membrane; integral to membrane; plasma membrane

Molecular Function: gamma-glutamyltransferase activity

Biological Process: amino acid metabolic process; leukotriene biosynthetic process; glutathione metabolic process; glutathione biosynthetic process; arachidonic acid metabolic process; leukotriene metabolic process; inflammatory response; proteolysis

Research Articles on GGT5

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Product Notes

The GGT5 ggt5 (Catalog #AAA967509) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-387. The amino acid sequence is listed below: MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL IRQQIDGRGD HQLSHYSLAE AWGHGTG. It is sometimes possible for the material contained within the vial of "Gamma-glutamyltransferase 5 (GGT5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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