Western Blot (WB)
(Western Blot analysis of GGT5 expression in transfected 293T cell line by GGT5 polyclonal antibody. Lane 1: GGTLA1 transfected lysate (64.57kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human GGTLA1 Polyclonal Antibody | anti-GGT5 antibody
GGTLA1 (Gamma-glutamyltransferase 5, Gamma-glutamyltranspeptidase 5, GGT 5, GGT5, Gamma-glutamyltransferase-like Activity 1, Gamma-glutamyl Transpeptidase-related Enzyme, GGT-rel)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of GGT5 expression in transfected 293T cell line by GGT5 polyclonal antibody. Lane 1: GGTLA1 transfected lysate (64.57kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of GGT5 expression in transfected 293T cell line by GGT5 polyclonal antibody. Lane 1: GGTLA1 transfected lysate (64.57kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesn't convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4).
Catalytic activity: A (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid.Glutathione + H2O = L-cysteinylglycine + L-glutamate.Leukotriene C4 + H2O = leukotriene D4 + L-glutamate.
Pathway: Sulfur metabolism; glutathione metabolism.Lipid metabolism; leukotriene D4 biosynthesis.
Subunit structure: Heterodimer composed of the light and heavy chains. The active site is located in the light chain
By similarity.
Subcellular location: Membrane; Single-pass type II membrane protein
By similarity.
Sequence similarities: Belongs to the gamma-glutamyltransferase family.
Sequence caution: The sequence CAB55910.1 differs from that shown. Reason: Frameshift at position 446.
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Product Notes
The GGT5 ggt5 (Catalog #AAA647334) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GGTLA1 (Gamma-glutamyltransferase 5, Gamma-glutamyltranspeptidase 5, GGT 5, GGT5, Gamma-glutamyltransferase-like Activity 1, Gamma-glutamyl Transpeptidase-related Enzyme, GGT-rel) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GGTLA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the GGT5 ggt5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MARGYGATVS LVLLGLGLAL AVIVLAVVLS RHQAPCGPQA FAHAAVAADS KVCSDIGRAI LQQQGSPVDA TIAALVCTSV VNPQSMGLGG GVIFTIYNVT TGKVEVINAR ETVPASHAPS LLDQCAQALP LGTGAQWIGV PGELRGYAEA HRRHGRLPWA QLFQPTIALL RGGHVVAPVL SRFLHNSILR PSLQASTLRQ LFFNGTEPLR PQDPLPWPAL ATTLETVATE GVEVFYTGRL GQMLVEDIAK EGSQLTLQDL AKFQPEVVDA LEVPLGDYTL YSPPPPAGGA ILSFILNVLR GFNFSTESMA RPEGRVNVYH HLVETLKFAK GQRWRLGDPR SHPKLQNASR DLLGETLAQL IRQQIDGRGD HQLSHYSLAE AWGHGTGTSH VSVLGEDGSA VAATSTINTP FGAMVYSPRT GIILNNELLD LCERCPRGSG TTPSPAVSGD RVGGAPGRCW PPVPGERSPS SMVPSILINK AQGSKLVIGG AGGELIISAV AQAIMSKLWL GFDLRAAIAA PILHVNSKGC VEYEPNFSQE VQRGLQDRGQ NQTQRPFFLN VVQAVSQEGA CVYAVSDLRK SGEAAGY. It is sometimes possible for the material contained within the vial of "GGTLA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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