Rabbit anti-Human MUC17 Polyclonal Antibody | anti-MUC17 antibody
MUC17 Antibody
Gene Names
MUC17; MUC3
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
MUC17; Polyclonal Antibody; MUC17 Antibody; Membrane mucin MUC17; MUC-17; MUC-3; MUC17_HUMAN; Mucin 17; cell surface associated; Mucin-17; Secreted mucin MUC17; Small intestinal mucin MUC3; Small intestinal mucin-3; anti-MUC17 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
MUC17 Antibody detects endogenous levels of total MUC17.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-MUC17 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Post Translational Modifications
Probably cleaved within the SEA domain.N-glycosylated. Contains high mannose and complex-type glycans. The forms containing the complex type glycans localize to the cell surface. Not O-glycosylated.
Subunit Structure
Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization.
Tissue Specificity
Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers.
Function
Probably plays a role in maintaining homeostasis on mucosal surfaces.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-MUC17 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
451,741 Da
NCBI Official Full Name
mucin-17
NCBI Official Synonym Full Names
mucin 17, cell surface associated
NCBI Official Symbol
MUC17
NCBI Official Synonym Symbols
MUC3
NCBI Protein Information
mucin-17; MUC-3; MUC-17; OTTHUMP00000211331; membrane mucin MUC17; secreted mucin MUC17; small intestinal mucin-3; small intestinal mucin MUC3
UniProt Protein Name
Mucin-17
Protein Family
UniProt Gene Name
MUC17
UniProt Synonym Gene Names
MUC3
UniProt Entry Name
MUC17_HUMAN
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Product Notes
The MUC17 muc17 (Catalog #AAA9629179) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MUC17 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MUC17 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the MUC17 muc17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MUC17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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