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Western Blot (WB) (Western blot analysis of LSM2 using Jurkat whole cell lysates)

Rabbit LSM2 Polyclonal Antibody | anti-LSM2 antibody

LSM2 Antibody

Gene Names
LSM2; G7B; snRNP; C6orf28; YBL026W
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
LSM2; Polyclonal Antibody; LSM2 Antibody; C6orf28; Chromosome 6 open reading frame 28; G7b; LSM 2; Lsm2; LSM2 homolog; U6 small nuclear RNA associated (S. cerevisiae); Lsm2 protein; LSM2_HUMAN; OTTHUMP00000029159; Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP; snRNP core Sm like protein Sm x5; snRNP core Sm-like protein Sm-x5; U6 snRNA associated Sm like protein LSm2; U6 snRNA-associated Sm-like protein LSm2; YBL026W; anti-LSM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
LSM2 antibody detects endogenous levels of total LSM2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
95
Applicable Applications for anti-LSM2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human LSM2
Subcellular Location
Nucleus
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of LSM2 using Jurkat whole cell lysates)

Western Blot (WB) (Western blot analysis of LSM2 using Jurkat whole cell lysates)
Related Product Information for anti-LSM2 antibody
Function: Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.
Subunit Structure: Identified in the spliceosome C complex. LSm subunits form a heteromer with a doughnut shape.
Similarity: Belongs to the snRNP Sm proteins family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 11 kDa
Predicted: 11 kDa
NCBI Official Full Name
U6 snRNA-associated Sm-like protein LSm2
NCBI Official Synonym Full Names
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
NCBI Official Symbol
LSM2
NCBI Official Synonym Symbols
G7B; snRNP; C6orf28; YBL026W
NCBI Protein Information
U6 snRNA-associated Sm-like protein LSm2
UniProt Protein Name
U6 snRNA-associated Sm-like protein LSm2
Protein Family
UniProt Gene Name
LSM2
UniProt Synonym Gene Names
C6orf28; G7B

NCBI Description

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]

Uniprot Description

Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).

Research Articles on LSM2

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Product Notes

The LSM2 lsm2 (Catalog #AAA9610293) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LSM2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LSM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the LSM2 lsm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LSM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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