Western Blot (WB)
(Western blot analysis of DDAH2 on different tissue lysates using anti-DDAH2 antibody at 1/2, 000 dilution. Positive control: Lane 1: Rat heart Lane 2: Mouse heart Lane 3: Mouse lung Lane 4: Human lung)
Rabbit DDAH2 Monoclonal Antibody | anti-DDAH2 antibody
DDAH2 Antibody
IP: 1:10-:50
Western Blot (WB)
(Western blot analysis of DDAH2 on different tissue lysates using anti-DDAH2 antibody at 1/2, 000 dilution. Positive control: Lane 1: Rat heart Lane 2: Mouse heart Lane 3: Mouse lung Lane 4: Human lung)
Western Blot (WB)
(Western blot analysis of DDAH2 on different tissue lysates using anti-DDAH2 antibody at 1/2, 000 dilution. Positive control: Lane 1: Rat heart Lane 2: Mouse heart Lane 3: Mouse lung Lane 4: Human lung)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014]
Uniprot Description
DDAH2: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. Belongs to the DDAH family.
Protein type: EC 3.5.3.18; Apoptosis; Hydrolase
Chromosomal Location of Human Ortholog: 6p21.3
Cellular Component: centrosome; mitochondrion; cytoplasm
Molecular Function: amino acid binding; protein binding; dimethylargininase activity; catalytic activity
Biological Process: positive regulation of nitric oxide biosynthetic process; citrulline metabolic process; arginine catabolic process; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; negative regulation of apoptosis
Research Articles on DDAH2
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Product Notes
The DDAH2 ddah2 (Catalog #AAA9436562) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDAH2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DDAH2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB: 1:2000-1:5000 IP: 1:10-:50. Researchers should empirically determine the suitability of the DDAH2 ddah2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDAH2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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