High affinity nerve growth factor receptor (Ntrk1) Recombinant Protein | Ntrk1 recombinant protein
Recombinant Rat High affinity nerve growth factor receptor (Ntrk1)
NCBI and Uniprot Product Information
NCBI Description
a protooncogene; receptor that binds to nerve growth factor (NGF) [RGD, Feb 2006]
Uniprot Description
TrkA: a receptor tyrosine kinase of the Trk family. High affinity receptor for nerve growth factor, neurotrophin-3 and neurotrophin-4/5 but not brain- derived neurotrophic factor. Known substrates include Shc, PI-3K, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system. Two splice variant isoforms have been described.
Protein type: Protein kinase, tyrosine (receptor); Protein kinase, TK; Kinase, protein; Membrane protein, integral; EC 2.7.10.1; Oncoprotein; TK group; Trk family
Cellular Component: cell surface; protein complex; late endosome membrane; integral to plasma membrane; early endosome; dendrite; Golgi membrane; cell soma; early endosome membrane; axon; cytoplasm; late endosome; plasma membrane; cytoplasmic vesicle; receptor complex
Molecular Function: neurotrophin p75 receptor binding; protein binding; protein homodimerization activity; nerve growth factor receptor activity; ephrin receptor binding; protein-tyrosine kinase activity; nerve growth factor binding; transmembrane receptor protein tyrosine kinase activity; kinase binding; ATP binding
Biological Process: circadian rhythm; response to nicotine; axon guidance; mechanoreceptor differentiation; peptidyl-tyrosine phosphorylation; nerve growth factor receptor signaling pathway; protein amino acid autophosphorylation; sensory perception of pain; olfactory nerve development; protein amino acid phosphorylation; positive regulation of synaptic transmission, glutamatergic; activation of NF-kappaB transcription factor; negative regulation of cell proliferation; sympathetic nervous system development; response to radiation; learning and/or memory; response to axon injury; negative regulation of neuron apoptosis; response to electrical stimulus; detection of temperature stimulus involved in sensory perception of pain; response to hydrostatic pressure; aging; response to drug; response to nutrient levels; nervous system development; Sertoli cell development; detection of mechanical stimulus involved in sensory perception of pain; positive regulation of angiogenesis; positive regulation of programmed cell death; response to ethanol; B cell differentiation; positive regulation of Ras protein signal transduction; response to activity
Research Articles on Ntrk1
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Product Notes
The Ntrk1 ntrk1 (Catalog #AAA953738) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 33-418. The amino acid sequence is listed below: AASCRETC CPVGPSGLRC TRAGTLNTLR GLRGAGNLTE LYVENQRDLQ RLEFEDLQGL GELRSLTIVK SGLRFVAPDA FHFTPRLSHL NLSSNALESL SWKTVQGLSL QDLTLSGNPL HCSCALLWLQ RWEQEDLCGV YTQKLQGSGS GDQFLPLGHN NSCGVPSVKI QMPNDSVEVG DDVFLQCQVE GQALQQADWI LTELEGTATM KKSGDLPSLG LTLVNVTSDL NKKNVTCWAE NDVGRAEVSV QVSVSFPASV HLGKAVEQHH WCIPFSVDGQ PAPSLRWFFN GSVLNETSFI FTQFLESALT NETMRHGCLR LNQPTHVNNG NYTLLAANPY GQAAASIMAA FMDNPFEFNP EDPIPVSFSP VDTNSTSRDP VEKKDETP. It is sometimes possible for the material contained within the vial of "High affinity nerve growth factor receptor (Ntrk1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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