Ephrin-B3 Recombinant Protein | EFNB3 recombinant protein
Recombinant mouse Ephrin-B3
NCBI and Uniprot Product Information
Uniprot Description
EFNB3: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. Belongs to the ephrin family.
Protein type: Cell development/differentiation; Ligand, receptor tyrosine kinase; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11 B3|11 42.8 cM
Cellular Component: plasma membrane
Molecular Function: ephrin receptor binding
Biological Process: adult walking behavior; axon choice point recognition; axon guidance; ephrin receptor signaling pathway; T cell costimulation
Research Articles on EFNB3
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Product Notes
The EFNB3 efnb3 (Catalog #AAA9420200) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length of Extracellular, 28-227aa. The Recombinant mouse Ephrin-B3 reacts with Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Ephrin-B3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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