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Testing Data (Gel: 6%SDS-PAGE Lysate: 40ug Skov3 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes)

Rabbit anti-Human, Mouse ZMIZ1 Polyclonal Antibody | anti-ZMIZ1 antibody

ZMIZ1 Antibody

Gene Names
ZMIZ1; MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Antigen affinity purification.
Synonyms
ZMIZ1; Polyclonal Antibody; ZMIZ1 Antibody; MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10; anti-ZMIZ1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total ZMIZ1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
2.8 mg/ml (varies by lot)
Sequence Length
1067
Applicable Applications for anti-ZMIZ1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the N terminal of human zinc finger, MIZ-type containing 1
Target Name
ZMIZ1
SDS-PAGE MW
115 kD
Preparation and Storage
Store at -20°C

Testing Data

(Gel: 6%SDS-PAGE Lysate: 40ug Skov3 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes)

Testing Data (Gel: 6%SDS-PAGE Lysate: 40ug Skov3 cell Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.)
Related Product Information for anti-ZMIZ1 antibody
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia.
Product Categories/Family for anti-ZMIZ1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
zinc finger MIZ domain-containing protein 1
NCBI Official Synonym Full Names
zinc finger, MIZ-type containing 1
NCBI Official Symbol
ZMIZ1
NCBI Official Synonym Symbols
MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10
NCBI Protein Information
zinc finger MIZ domain-containing protein 1
UniProt Protein Name
Zinc finger MIZ domain-containing protein 1
UniProt Gene Name
ZMIZ1
UniProt Synonym Gene Names
KIAA1224; RAI17; ZIMP10
UniProt Entry Name
ZMIZ1_HUMAN

NCBI Description

This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]

Uniprot Description

RAI17: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 10q22.3

Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm; nuclear speck

Molecular Function: zinc ion binding

Biological Process: heart morphogenesis; developmental growth; positive regulation of fibroblast proliferation; transcription, DNA-dependent; in utero embryonic development; vitellogenesis; artery morphogenesis; cell aging; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis

Research Articles on ZMIZ1

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Product Notes

The ZMIZ1 zmiz1 (Catalog #AAA9404009) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMIZ1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZMIZ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the ZMIZ1 zmiz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZMIZ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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