Western Blot (WB)
(Lanes:Lane 1: 50ug mouse retina extractLane 2: 50ug mouse prostate extractLane 3: 50ug mouse testis extractLane 4: 50ug mouse colon extractPrimary Antibody Dilution:1:1000Secondary Antibody:Anti-rabbit HRPSecondary Antibody Dilution:1:10,000Gene Name:ZMIZ1Submitted by:John Fu, UVA)
Rabbit ZMIZ1 Polyclonal Antibody | anti-ZMIZ1 antibody
ZMIZ1 antibody - N-terminal region
Western Blot (WB)
(Lanes:Lane 1: 50ug mouse retina extractLane 2: 50ug mouse prostate extractLane 3: 50ug mouse testis extractLane 4: 50ug mouse colon extractPrimary Antibody Dilution:1:1000Secondary Antibody:Anti-rabbit HRPSecondary Antibody Dilution:1:10,000Gene Name:ZMIZ1Submitted by:John Fu, UVA)
Western Blot (WB)
(Lanes:Lane 1: 50ug mouse retina extractLane 2: 50ug mouse prostate extractLane 3: 50ug mouse testis extractLane 4: 50ug mouse colon extractPrimary Antibody Dilution:1:1000Secondary Antibody:Anti-rabbit HRPSecondary Antibody Dilution:1:10,000Gene Name:ZMIZ1Submitted by:John Fu, UVA)
Western Blot (WB)
(WB Suggested Anti-ZMIZ1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate)
Western Blot (WB)
(WB Suggested Anti-ZMIZ1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: 293T cell lysate)
Target Description: ZMIZ1 increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Uniprot Description
RAI17: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 10q22.3
Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm; nuclear speck
Molecular Function: zinc ion binding
Biological Process: heart morphogenesis; developmental growth; positive regulation of fibroblast proliferation; transcription, DNA-dependent; in utero embryonic development; vitellogenesis; artery morphogenesis; cell aging; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis
Research Articles on ZMIZ1
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Product Notes
The ZMIZ1 zmiz1 (Catalog #AAA3204610) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZMIZ1 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's ZMIZ1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the ZMIZ1 zmiz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: MNSMDRHIQQ TNDRLQCIKQ HLQNPANFHN AATELLDWCG DPRAFQRPFE. It is sometimes possible for the material contained within the vial of "ZMIZ1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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