Mouse squamous cell carcinoma antigen recognized by T cells 3 ELISA Kit | SART3 elisa kit
Mouse Squamous cell carcinoma antigen recognized by T-cells 3, SART3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SART3: a ubiquitously expressed protein in proliferating cells. A component of the 7SK snRNP complex composed of P-TEFb (composed of CDK9 and CCNT1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs. Transiently associates with the U6 and U4/U6 snRNPs during the spliceosome cycle, helping to regenerate functional U4/U6 snRNPs complexes. Expressed in the nucleus of all of malignant tumor cell lines tested and the majority of cancer tissues with various histologies, including squamous cell carcinomas, adenocarcinomas, melanomas and leukemias. However, this protein is undetectable in the nucleus of nonmalignant cell lines or normal tissues, except for the testis. Expressed in the cytoplasm of all proliferating cells, including normal and malignant cells, but not in most cells of normal tissues, except for the testis and the fetal liver. Regulates Tat transactivation activity through direct interaction. May be a cellular factor for HIV-1 gene expression and viral replication. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Nuclear receptor co-regulator; Transcription regulation
Cellular Component: nucleoplasm; Cajal body; cytoplasm; intracellular; nucleus
Molecular Function: U6atac snRNA binding; nucleic acid binding; histone binding; RNA binding; nucleotide binding
Biological Process: RNA processing; nuclear mRNA splicing, via spliceosome; assembly of spliceosomal tri-snRNP; nucleosome assembly; regulation of gene expression; RNA splicing; cell morphogenesis; homeostasis of number of cells; mRNA processing
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Product Notes
The Mouse SART3 sart3 (Catalog #AAA9340495) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340495 ELISA Kit recognizes Mouse SART3. It is sometimes possible for the material contained within the vial of "squamous cell carcinoma antigen recognized by T cells 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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