Mouse dual specificity phosphatase 3 ELISA Kit | DUSP3 elisa kit
Mouse Dual specificity protein phosphatase 3, DUSP3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DUSP3: a non-receptor, dual-specificity phosphoprotein phosphatase (DUSP). Different members of the DUSP family show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP3 inactivates the mitogen-activated kinases Erk2 and Jnk and is phosphorylated by ZAP-70. Phosphorylation by ZAP-70 is required for DUSP3 to inhibit the Erk2-Elk-1 pathway.
Protein type: EC 3.1.3.16; Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, dual-specificity
Cellular Component: nucleoplasm; cytoplasm; immunological synapse; nucleus; cytosol
Molecular Function: MAP kinase phosphatase activity; hydrolase activity; phosphoric monoester hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; phosphoprotein phosphatase activity; protein kinase binding
Biological Process: negative regulation of JNK cascade; dephosphorylation; negative regulation of MAPKKK cascade; in utero embryonic development; negative regulation of T cell receptor signaling pathway; protein amino acid dephosphorylation; positive regulation of mitotic cell cycle; negative regulation of T cell activation; inactivation of MAPK activity
Research Articles on DUSP3
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Product Notes
The Mouse DUSP3 dusp3 (Catalog #AAA9337262) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337262 ELISA Kit recognizes Mouse DUSP3. It is sometimes possible for the material contained within the vial of "dual specificity phosphatase 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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