Mouse calpain 2, (m/II) large subunit ELISA Kit | CAPN2 elisa kit

Mouse Calpain-2 Catalytic subunit, CAPN2 ELISA Kit

Gene Names

Capn2; Capa2; Capa-2; AI326419; m-calpin; m-calpain

Reactivity

Mouse

Synonyms

calpain 2; (m/II) large subunit; Mouse Calpain-2 Catalytic subunit; CAPN2 ELISA Kit; Mouse Calpain-2 catalytic subunit (CAPN2) ELISA kit; CANP2; CANPL2; CANPml; FLJ39928; mCANP; M-calpain; calcium-activated neutral proteinase; large [catalytic] subunit; large subunit; calpain M-type; calpain; large polypepti; CAPN2 elisa kit

Ordering
Cat. Num. AAA9332534 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Mouse

Preparation and Storage

Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #

157951598

NCBI GeneID

12334

NCBI Accession #

NP_033924.2

NCBI GenBank Nucleotide #

NM_009794.3

UniProt Accession #

O08529; O35518; O54843

Molecular Weight

79,872 Da

NCBI Official Full Name

calpain-2 catalytic subunit

NCBI Official Synonym Full Names

calpain 2

NCBI Official Symbol

Capn2

NCBI Official Synonym Symbols

Capa2; Capa-2; AI326419; m-calpin; m-calpain

NCBI Protein Information

calpain-2 catalytic subunit; CALP80; CANP 2; calpain M-type; millimolar-calpain; cysteine proteinase; calpain-2 large subunit; m-calpain large subunit; 80 kDa M-calpain subunit; m-calpain 80 kDa large subunit; calcium-activated neutral proteinase 2

UniProt Protein Name

Calpain-2 catalytic subunit

Protein Family

Calpain

UniProt Gene Name

Capn2

UniProt Synonym Gene Names

CALP80; CANP 2; M-calpain

UniProt Entry Name

CAN2_MOUSE

Uniprot Description

CAPN2: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Forms a heterodimer with a small (regulatory) subunit (CAPNS1). Ubiquitous. Activated by 200-1000 micromolar concentrations of calcium and inhibited by calpastatin. Belongs to the peptidase C2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.53; Motility/polarity/chemotaxis; Protease

Cellular Component: Golgi apparatus; focal adhesion; lysosome; endoplasmic reticulum; dendrite; pseudopodium; cytosol; lipid raft; membrane; cytoplasm; plasma membrane; intracellular; chromatin; nucleus

Molecular Function: peptidase activity; hydrolase activity; protein heterodimerization activity; metal ion binding; cytoskeletal protein binding; calcium-dependent cysteine-type endopeptidase activity; calcium ion binding; cysteine-type peptidase activity

Biological Process: protein autoprocessing; blastocyst development; proteolysis; myoblast fusion; regulation of cytoskeleton organization and biogenesis

Research Articles on CAPN2

1. extrasynaptic NMDAR-coupled m-calpain activation is neurodegenerative

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Product Notes

The Mouse CAPN2 capn2 (Catalog #AAA9332534) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9332534 ELISA Kit recognizes Mouse CAPN2. It is sometimes possible for the material contained within the vial of "calpain 2, (m/II) large subunit, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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