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Western Blot (WB) (Western Blot; Sample: Recombinant GLVR1, Human.)

Rabbit anti-Human Gibbon Ape Leukemia Virus Receptor 1 (GLVR1) Polyclonal Antibody | anti-GLVR1 antibody

Polyclonal Antibody to Gibbon Ape Leukemia Virus Receptor 1 (GLVR1)

Gene Names
SLC20A1; PIT1; GLVR1; PiT-1; Glvr-1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunoprecipitation
Purity
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Synonyms
Gibbon Ape Leukemia Virus Receptor 1 (GLVR1); Polyclonal Antibody; Polyclonal Antibody to Gibbon Ape Leukemia Virus Receptor 1 (GLVR1); SLC20A1; PIT1; Glvr-1; PiT-1; Sodium-Dependent Phosphate Transporter 1; Solute Carrier Family 20 Member 1; Leukemia virus receptor 1 homolog; Phosphate transporter 1; anti-GLVR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against GLVR1. It has been selected for its ability to recognize GLVR1 in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Form/Format
Liquid; PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Concentration
500ug/ml (varies by lot)
Sequence
Cys251~Glu510
Applicable Applications for anti-GLVR1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
Application Notes
WB: 0.5-2ug/mL
IHC: 5-20ug/mL
ICC: 5-20ug/mL
Immunogen Sequence
Cys251~Glu510
Cross Reactivity
Human
Conjugation
None
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Western Blot (WB)

(Western Blot; Sample: Recombinant GLVR1, Human.)

Western Blot (WB) (Western Blot; Sample: Recombinant GLVR1, Human.)

Immunohistochemistry (IHC)

(DAB staining on fromalin fixed paraffin- embedded stomach tissue)

Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin- embedded stomach tissue)
Product Categories/Family for anti-GLVR1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
679
NCBI Official Full Name
Sodium-dependent phosphate transporter 1
NCBI Official Synonym Full Names
solute carrier family 20 (phosphate transporter), member 1
NCBI Official Symbol
SLC20A1
NCBI Official Synonym Symbols
PIT1; GLVR1; PiT-1; Glvr-1
NCBI Protein Information
sodium-dependent phosphate transporter 1; leukemia virus receptor 1 homolog; solute carrier family 20 member 1; gibbon ape leukemia virus receptor 1
UniProt Protein Name
Sodium-dependent phosphate transporter 1
UniProt Gene Name
SLC20A1
UniProt Synonym Gene Names
GLVR1; PIT1; GLVR-1; PiT-1
UniProt Entry Name
S20A1_HUMAN

NCBI Description

The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011]

Uniprot Description

SLC20A1: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV). Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: signal transducer activity; high affinity inorganic phosphate:sodium symporter activity; receptor activity; sodium:phosphate symporter activity; inorganic phosphate transmembrane transporter activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; transport; ion transport; signal transduction; transmembrane transport; phosphate metabolic process

Research Articles on GLVR1

Similar Products

Product Notes

The GLVR1 slc20a1 (Catalog #AAA2112383) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Gibbon Ape Leukemia Virus Receptor 1 (GLVR1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Gibbon Ape Leukemia Virus Receptor 1 (GLVR1) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP). WB: 0.5-2ug/mL IHC: 5-20ug/mL ICC: 5-20ug/mL. Researchers should empirically determine the suitability of the GLVR1 slc20a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Cys251~Glu 510. It is sometimes possible for the material contained within the vial of "Gibbon Ape Leukemia Virus Receptor 1 (GLVR1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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