Human RAB11 family interacting protein 3 (class II) ELISA Kit | RAB11FIP3 elisa kit
Human Rab11 family-interacting protein 3, RAB11FIP3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
Uniprot Description
RAB11FIP3: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nucleoplasm; centrosome; recycling endosome; intercellular bridge; intracellular membrane-bound organelle; recycling endosome membrane; microtubule organizing center; midbody; cytosol; endosome; cleavage furrow
Molecular Function: ADP-ribosylation factor binding; protein binding; protein homodimerization activity; calcium ion binding; Rab GTPase binding
Biological Process: vesicle-mediated transport; organelle organization and biogenesis; cytokinesis; endocytic recycling
Research Articles on RAB11FIP3
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Product Notes
The Human RAB11FIP3 rab11fip3 (Catalog #AAA9331875) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331875 ELISA Kit recognizes Human RAB11FIP3. It is sometimes possible for the material contained within the vial of "RAB11 family interacting protein 3 (class II), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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