Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using RAB11FIP3 antibody.)
Rabbit anti-Human RAB11FIP3 Polyclonal Antibody | anti-RAB11FIP3 antibody
RAB11FIP3 Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using RAB11FIP3 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using RAB11FIP3 antibody.)
NCBI and Uniprot Product Information
NCBI Description
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]
Uniprot Description
RAB11FIP3: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nucleoplasm; centrosome; recycling endosome; intercellular bridge; intracellular membrane-bound organelle; recycling endosome membrane; microtubule organizing center; midbody; cytosol; endosome; cleavage furrow
Molecular Function: ADP-ribosylation factor binding; protein binding; protein homodimerization activity; calcium ion binding; Rab GTPase binding
Biological Process: vesicle-mediated transport; organelle organization and biogenesis; cytokinesis; endocytic recycling
Research Articles on RAB11FIP3
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Product Notes
The RAB11FIP3 rab11fip3 (Catalog #AAA9403497) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAB11FIP3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RAB11FIP3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:50~1:100. Researchers should empirically determine the suitability of the RAB11FIP3 rab11fip3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB11FIP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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