Human zinc finger protein 703 ELISA Kit | ZNF703 elisa kit
Human Zinc finger protein 703, ZNF703 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ZNF703: Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Regulates cell adhesion, migration and proliferation. May be required for segmental gene expression during hindbrain development. Luminal B breast cancers are the clinically more aggressive estrogen receptor-positive tumors. Amplification of a distal 8p12 locus occurs in around one third of the cases and ZNF703 is the single gene within the minimal amplicon. Amplification of the gene correlates with its protein expression in tumor cells. ZNF703 is a classical breast cancer oncogene since it is able to transform non-malignant cells and increase cellular proliferation. Belongs to the Elbow/Noc family.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 8p11.23
Cellular Component: protein complex; nuclear matrix; cytoplasm; nucleus
Molecular Function: protein binding; nucleic acid binding; metal ion binding
Biological Process: regulation of transforming growth factor beta receptor signaling pathway; transcription, DNA-dependent; regulation of transcription, DNA-dependent; regulation of cell cycle; negative regulation of homotypic cell-cell adhesion; positive regulation of cell proliferation; positive regulation of mammary gland epithelial cell proliferation; negative regulation of transcription, DNA-dependent; positive regulation of cell migration
Research Articles on ZNF703
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Product Notes
The Human ZNF703 znf703 (Catalog #AAA9327114) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327114 ELISA Kit recognizes Human ZNF703. It is sometimes possible for the material contained within the vial of "zinc finger protein 703, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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