Human EH domain binding protein 1 ELISA Kit | EHBP1 elisa kit
Human EH domain-binding protein 1, EHBP1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Uniprot Description
EHBP1: May play a role in actin reorganization. Links clathrin- mediated endocytosis to the actin cytoskeleton. Defects in EHBP1 are a cause of susceptibility to prostate cancer hereditary type 12 (HPC12). It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 2p15
Cellular Component: cytoplasm; plasma membrane
Disease: Prostate Cancer, Hereditary, 12
Research Articles on EHBP1
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Product Notes
The Human EHBP1 ehbp1 (Catalog #AAA9322835) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322835 ELISA Kit recognizes Human EHBP1. It is sometimes possible for the material contained within the vial of "EH domain binding protein 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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