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Western Blot (WB) (All lanes : Anti-FDFT1 Antibody (C-term) at 1:1000 dilutionLane 1: Jurkat whole cell lysateLane 2: HepG2 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human FDFT1 Polyclonal Antibody | anti-FDFT1 antibody

FDFT1 Antibody (C-term)

Gene Names
FDFT1; SS; SQS; DGPT; ERG9; SQSD
Reactivity
Human
Applications
Western Blot, ELISA
Synonyms
FDFT1; Polyclonal Antibody; FDFT1 Antibody (C-term); Squalene synthase; SQS; SS; FPP:FPP farnesyltransferase; Farnesyl-diphosphate farnesyltransferase; anti-FDFT1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Specificity
This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.
Sequence Length
417
Applicable Applications for anti-FDFT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000
Antigen Source
Human
Antigen Region
332-361
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-FDFT1 Antibody (C-term) at 1:1000 dilutionLane 1: Jurkat whole cell lysateLane 2: HepG2 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-FDFT1 Antibody (C-term) at 1:1000 dilutionLane 1: Jurkat whole cell lysateLane 2: HepG2 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-FDFT1 antibody
Description: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Background: This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Product Categories/Family for anti-FDFT1 antibody
References
Chalasani, N., et al. Gastroenterology 139(5):1567-1576(2010). Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Kovanen, L., et al. Alcohol Alcohol. 45(4):303-311(2010). Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010). Sjoholm, L.K., et al. J Circadian Rhythms 8, 1 (2010).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48115
NCBI Official Full Name
squalene synthase isoform 1
NCBI Official Synonym Full Names
farnesyl-diphosphate farnesyltransferase 1
NCBI Official Symbol
FDFT1
NCBI Official Synonym Symbols
SS; SQS; DGPT; ERG9; SQSD
NCBI Protein Information
squalene synthase
UniProt Protein Name
Squalene synthase
UniProt Gene Name
FDFT1
UniProt Synonym Gene Names
SQS; SS
UniProt Entry Name
FDFT_HUMAN

NCBI Description

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]

Uniprot Description

FDFT1: a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]

Protein type: EC 2.5.1.21; Endoplasmic reticulum; Lipid Metabolism - steroid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase; Transferase

Chromosomal Location of Human Ortholog: 8p23.1-p22

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane

Molecular Function: farnesyl-diphosphate farnesyltransferase activity

Biological Process: cholesterol biosynthetic process; farnesyl diphosphate metabolic process; steroid biosynthetic process

Research Articles on FDFT1

Similar Products

Product Notes

The FDFT1 fdft1 (Catalog #AAA9232096) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FDFT1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FDFT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the FDFT1 fdft1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FDFT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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