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PGLYRP2 blocking peptide

PGLYRP2 Blocking Peptide (N-Term)

Gene Names
PGLYRP2; tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
Synonyms
PGLYRP2; PGLYRP2 Blocking Peptide (N-Term); N-acetylmuramoyl-L-alanine amidase; 3.5.1.28; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L; PGLYRPL; PGRPL; PGLYRP2 blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 95-107 of HUMAN PGLYRP2
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
576
Cellular Location
Secreted. Membrane.
Tissue Location
Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PGLYRP2 blocking peptide
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
68,000 Da
NCBI Official Full Name
N-acetylmuramoyl-L-alanine amidase
NCBI Official Synonym Full Names
peptidoglycan recognition protein 2
NCBI Official Symbol
PGLYRP2
NCBI Official Synonym Symbols
tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
NCBI Protein Information
N-acetylmuramoyl-L-alanine amidase
UniProt Protein Name
N-acetylmuramoyl-L-alanine amidase
UniProt Gene Name
PGLYRP2
UniProt Synonym Gene Names
PGLYRPL; PGRPL; PGRP-L
UniProt Entry Name
PGRP2_HUMAN

NCBI Description

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

Uniprot Description

PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Hydrolase; Secreted; EC 3.5.1.28; Receptor, misc.

Chromosomal Location of Human Ortholog: 19p13.12

Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity

Biological Process: defense response to Gram-positive bacterium; detection of bacterium

Research Articles on PGLYRP2

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Product Notes

The PGLYRP2 pglyrp2 (Catalog #AAA9230599) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PGLYRP2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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