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Western Blot (WB) (Anti-PGLYRP2 Antibody (N-Term) at 1:2000 dilution + human placenta lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human PGLYRP2 Polyclonal Antibody | anti-PGLYRP2 antibody

PGLYRP2 Antibody (N-Term)

Gene Names
PGLYRP2; tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
Reactivity
Human
Applications
Western Blot
Synonyms
PGLYRP2; Polyclonal Antibody; PGLYRP2 Antibody (N-Term); Purified Rabbit Polyclonal Antibody (Pab); N-acetylmuramoyl-L-alanine amidase; 3.5.1.28; Peptidoglycan recognition protein 2; Peptidoglycan recognition protein long; PGRP-L; PGLYRPL; PGRPL; anti-PGLYRP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Sequence Length
576
Applicable Applications for anti-PGLYRP2 antibody
Western Blot (WB)
Application Notes
WB~~1:2000
Antigen Type
Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-PGLYRP2 Antibody (N-Term) at 1:2000 dilution + human placenta lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-PGLYRP2 Antibody (N-Term) at 1:2000 dilution + human placenta lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-PGLYRP2 antibody
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
Product Categories/Family for anti-PGLYRP2 antibody
References
Liu C.,et al.J. Biol. Chem. 276:34686-34694(2001). Yamada S.,et al.Oncogene 23:5901-5911(2004). Clark H.F.,et al.Genome Res. 13:2265-2270(2003). Ota T.,et al.Nat. Genet. 36:40-45(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,000 Da
NCBI Official Full Name
N-acetylmuramoyl-L-alanine amidase
NCBI Official Synonym Full Names
peptidoglycan recognition protein 2
NCBI Official Symbol
PGLYRP2
NCBI Official Synonym Symbols
tagL; PGRPL; PGRP-L; PGLYRPL; HMFT0141; TAGL-like; tagl-beta; tagL-alpha
NCBI Protein Information
N-acetylmuramoyl-L-alanine amidase
UniProt Protein Name
N-acetylmuramoyl-L-alanine amidase
UniProt Gene Name
PGLYRP2
UniProt Synonym Gene Names
PGLYRPL; PGRPL; PGRP-L
UniProt Entry Name
PGRP2_HUMAN

NCBI Description

This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. This protein hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell wall glycopeptides, and thus may play a scavenger role by digesting biologically active peptidoglycan into biologically inactive fragments. [provided by RefSeq, Sep 2011]

Uniprot Description

PGLYRP2: May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Hydrolase; Secreted, signal peptide; EC 3.5.1.28; Secreted

Chromosomal Location of Human Ortholog: 19p13.12

Cellular Component: intracellular; membrane

Molecular Function: N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding

Biological Process: defense response to Gram-positive bacterium; detection of bacterium; innate immune response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation during immune response; pattern recognition receptor signaling pathway; peptide amidation; peptidoglycan catabolic process; regulation of inflammatory response

Research Articles on PGLYRP2

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Product Notes

The PGLYRP2 pglyrp2 (Catalog #AAA9216949) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGLYRP2 Antibody (N-Term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGLYRP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB~~1:2000. Researchers should empirically determine the suitability of the PGLYRP2 pglyrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGLYRP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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