FXC1 Blocking Peptide | TIMM10B blocking peptide

FXC1 Blocking Peptide (N-term)

• Gene Names: TIMM10B; FXC1; Tim9b; TIM10B
• Synonyms: FXC1; FXC1 Blocking Peptide (N-term); Mitochondrial import inner membrane translocase subunit Tim10 B; Fracture callus protein 1; FxC1; Mitochondrial import inner membrane translocase subunit Tim9 B; TIMM10B; Tim10b; TIM9B; TIMM9B; TIMM10B blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 15-28 of HUMAN TIMM10B
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 103

• Cellular Location: Mitochondrion inner membrane; Peripheral membrane protein
• Tissue Location: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TIMM10B blocking peptide

Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.

NCBI and Uniprot Product Information

• NCBI GI #: 12230190
• NCBI GeneID: 26515
• UniProt Accession #: Q9Y5J6; Q96FF3
• Molecular Weight: 11,586 Da
• NCBI Official Full Name: Mitochondrial import inner membrane translocase subunit Tim10 B
• NCBI Official Synonym Full Names: translocase of inner mitochondrial membrane 10 homolog B (yeast)
• NCBI Official Symbol: TIMM10B
• NCBI Official Synonym Symbols: FXC1; Tim9b; TIM10B
• NCBI Protein Information: mitochondrial import inner membrane translocase subunit Tim10 B
• UniProt Protein Name: Mitochondrial import inner membrane translocase subunit Tim10 B
• Protein Family: Mitochondrial import inner membrane translocase
• UniProt Gene Name: TIMM10B
• UniProt Synonym Gene Names: FXC1; TIM9B; TIMM9B; Tim10b
• UniProt Entry Name: T10B_HUMAN

NCBI Description

FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]

Uniprot Description

TIMM10B: Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. Belongs to the small Tim family.

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial intermembrane space protein transporter complex

Biological Process: cell-matrix adhesion; protein targeting to mitochondrion