MAZ blocking peptide
MAZ Blocking Peptide (Center)
Gene Names
MAZ; PUR1; ZF87; Pur-1; SAF-1; SAF-2; SAF-3; Zif87; ZNF801
Synonyms
MAZ; MAZ Blocking Peptide (Center); Myc-associated zinc finger protein; MAZI; Pur-1; Purine-binding transcription factor; Serum amyloid A-activating factor-1; SAF-1; Transcription factor Zif87; ZF87; Zinc finger protein 801; ZNF801; MAZ blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 315-327 of HUMAN MAZ
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
477
Cellular Location
Nucleus. Note: In brains of Alzheimer disease patients, present in a plaque- like structures
Tissue Location
Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MAZ blocking peptide
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
17,763 Da
NCBI Official Full Name
Myc-associated zinc finger protein
NCBI Official Synonym Full Names
MYC associated zinc finger protein
NCBI Official Symbol
MAZ
NCBI Official Synonym Symbols
PUR1; ZF87; Pur-1; SAF-1; SAF-2; SAF-3; Zif87; ZNF801
NCBI Protein Information
myc-associated zinc finger protein
UniProt Protein Name
Myc-associated zinc finger protein
Protein Family
UniProt Gene Name
MAZ
UniProt Synonym Gene Names
ZNF801; MAZI; SAF-1
UniProt Entry Name
MAZ_HUMAN
Uniprot Description
MAZ: a myc-associated zinc finger protein. An inflammation-responsive transcription factor with dual roles in transcription initiation and termination. Binds to two sites within the c-myc promoter. Also binds to multiple G/C-rich sites within the promoter of the SP1 family of transcription factors. Expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas.
Protein type: C2H2-type zinc finger protein; RNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 16p11.2
Molecular Function: protein binding
Biological Process: termination of RNA polymerase II transcription; transcription initiation from RNA polymerase II promoter
Research Articles on MAZ
Similar Products
Product Notes
The MAZ maz (Catalog #AAA9230395) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MAZ, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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