ZNF281 blocking peptide

ZNF281 Blocking Peptide (Center)

Gene Names

ZNF281; ZBP-99; ZNP-99

Synonyms

ZNF281; ZNF281 Blocking Peptide (Center); Zinc finger protein 281; GC-box-binding zinc finger protein 1; Transcription factor ZBP-99; Zinc finger DNA-binding protein 99; GZP1; ZBP99; ZNF281 blocking peptide

Ordering

Specificity

The synthetic peptide sequence is selected from aa 416-430 of HUMAN ZNF281

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.

Sequence Length

895

Cellular Location

Nucleus.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ZNF281 blocking peptide

Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes.

NCBI and Uniprot Product Information

NCBI GI #

13124664

NCBI GeneID

23528

UniProt Accession #

Q9Y2X9; Q5RKW5; Q9NY92; A6NF48; B3KMX2

Molecular Weight

93,232 Da

NCBI Official Full Name

Zinc finger protein 281

NCBI Official Synonym Full Names

zinc finger protein 281

NCBI Official Symbol

ZNF281

NCBI Official Synonym Symbols

ZBP-99; ZNP-99

NCBI Protein Information

zinc finger protein 281

UniProt Protein Name

Zinc finger protein 281

Protein Family

Zinc finger protein

UniProt Gene Name

ZNF281

UniProt Synonym Gene Names

GZP1; ZBP99

UniProt Entry Name

ZN281_HUMAN

Uniprot Description

ZNF281: Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity

Biological Process: embryonic body morphogenesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; stem cell differentiation

Research Articles on ZNF281

1. High ZNF281 expression is associated with colon and breast cancer.

Similar Products

Product Notes

The ZNF281 znf281 (Catalog #AAA9229744) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZNF281, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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ZNF281 blocking peptide