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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7002607 at dilution of 1:100)

Rabbit anti-Human ZNF281 Polyclonal Antibody | anti-ZNF281 antibody

ZNF281 Antibody

Gene Names
ZNF281; ZBP-99; ZNP-99
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%,Protein G purified
Synonyms
ZNF281; Polyclonal Antibody; ZNF281 Antibody; Zinc finger protein 281; GC-box-binding zinc finger protein 1; Transcription factor ZBP-99; Zinc finger DNA-binding protein 99; GZP1; ZBP99; anti-ZNF281 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%,Protein G purified
Form/Format
Liquid
Sequence Length
895
Applicable Applications for anti-ZNF281 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Immunogen
Recombinant human Zinc finger protein 281 protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-103949 / sc-103950 / sc-98280
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7002607 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7002607 at dilution of 1:100)
Related Product Information for anti-ZNF281 antibody
Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs. Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
93,232 Da
NCBI Official Full Name
zinc finger protein 281 isoform 1
NCBI Official Synonym Full Names
zinc finger protein 281
NCBI Official Symbol
ZNF281
NCBI Official Synonym Symbols
ZBP-99; ZNP-99
NCBI Protein Information
zinc finger protein 281
UniProt Protein Name
Zinc finger protein 281
Protein Family
UniProt Gene Name
ZNF281
UniProt Synonym Gene Names
GZP1; ZBP99
UniProt Entry Name
ZN281_HUMAN

Uniprot Description

ZNF281: Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin and ornithine decarboxylase. Binds to the G-rich box in the enhancer region of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity

Biological Process: embryonic body morphogenesis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; stem cell differentiation

Research Articles on ZNF281

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Product Notes

The ZNF281 znf281 (Catalog #AAA7002607) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF281 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF281 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ZNF281 znf281 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF281, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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