ZNRF2 blocking peptide
ZNRF2 Blocking Peptide (N-term)
Gene Names
ZNRF2; RNF202
Synonyms
ZNRF2; ZNRF2 Blocking Peptide (N-term); E3 ubiquitin-protein ligase ZNRF2; 632-; Protein Ells2; RING finger protein 202; Zinc/RING finger protein 2; RNF202; ZNRF2 blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 2-16 of HUMAN ZNRF2
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
242
Cellular Location
Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein. Note: Present in presynaptic plasma membranes in neurons
Tissue Location
Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ZNRF2 blocking peptide
May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
24,115 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase ZNRF2
NCBI Official Synonym Full Names
zinc and ring finger 2, E3 ubiquitin protein ligase
NCBI Official Symbol
ZNRF2
NCBI Official Synonym Symbols
RNF202
NCBI Protein Information
E3 ubiquitin-protein ligase ZNRF2
UniProt Protein Name
E3 ubiquitin-protein ligase ZNRF2
Protein Family
UniProt Gene Name
ZNRF2
UniProt Synonym Gene Names
RNF202
UniProt Entry Name
ZNRF2_HUMAN
Uniprot Description
ZNRF2: May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Protein type: Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; EC 6.3.2.-; Ligase
Chromosomal Location of Human Ortholog: 7p14.3
Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; plasma membrane; protein complex
Molecular Function: ubiquitin-protein ligase activity
Biological Process: protein polyubiquitination
Research Articles on ZNRF2
Similar Products
Product Notes
The ZNRF2 znrf2 (Catalog #AAA9229386) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZNRF2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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