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PIP5K1B blocking peptide

PIP5K1B Antibody (N-term) Blocking Peptide

Gene Names
PIP5K1B; MSS4; STM7
Synonyms
PIP5K1B; PIP5K1B Antibody (N-term) Blocking Peptide; Phosphatidylinositol 4-phosphate 5-kinase type-1 beta; PIP5K1-beta; PtdIns(4)P-5-kinase 1 beta; Phosphatidylinositol 4-phosphate 5-kinase type I beta; PIP5KIbeta; Protein STM-7; Type I phosphatidylinositol 4-phosphate 5-kinase beta; STM7; PIP5K1B blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the N-term region of human PIP5K1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Sequence Length
540
Cellular Location
Endomembrane system. Note: Associated with membranes.
Tissue Location
Detected in heart, pancreas, brain, kidney, skeletal muscle and lung.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PIP5K1B blocking peptide
Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
56,951 Da
NCBI Official Full Name
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
NCBI Official Synonym Full Names
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
NCBI Official Symbol
PIP5K1B
NCBI Official Synonym Symbols
MSS4; STM7
NCBI Protein Information
phosphatidylinositol 4-phosphate 5-kinase type-1 beta
UniProt Protein Name
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
UniProt Gene Name
PIP5K1B
UniProt Synonym Gene Names
STM7; PIP5K1-beta; PtdIns(4)P-5-kinase 1 beta; PIP5KIbeta
UniProt Entry Name
PI51B_HUMAN

Uniprot Description

PIP5K1B: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.68; Kinase, lipid

Chromosomal Location of Human Ortholog: 9q13

Cellular Component: cytosol; uropod

Molecular Function: 1-phosphatidylinositol-3-phosphate 5-kinase activity; 1-phosphatidylinositol-4-phosphate 5-kinase activity; protein binding

Biological Process: phosphatidylinositol biosynthetic process; regulation of phosphoinositide 3-kinase cascade

Research Articles on PIP5K1B

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Product Notes

The PIP5K1B pip5k1b (Catalog #AAA9227479) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PIP5K1B, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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