SCDGFB Blocking Peptide | Pdgfd blocking peptide
SCDGFB Antibody (Center) Blocking Peptide
Gene Names
Pdgfd; Scdgfb; rSCDGF-B
Synonyms
SCDGFB; SCDGFB Antibody (Center) Blocking Peptide; Platelet-derived growth factor D; PDGF-D; Iris-expressed growth factor; Spinal cord-derived growth factor B; SCDGF-B; latent form; PDGFD latent form; receptor-binding form; PDGFD receptor-binding form; Pdgfd; Iegf; Scdgfb; Pdgfd blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the Center region of human SCDGFB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Sequence Length
370
Cellular Location
Secreted. Note: Released by platelets upon wounding.
Tissue Location
Widely expressed. Expressed at high levels in the kidney, adrenal glands, eye and CNS. In the kidney the localization is confined to arterial and arteriolar vascular smooth muscle cells and is also detected at low levels in the glomeruli In the eye in the anterior segment it is localized to the iris and ciliary body. In the retina localizes intensely to the outer plexiform layer, which contains photoreceptor axons and the synaptic layer between photoreceptors and second order neurons. In the spinal cord, prominently expressed in the motorneurons.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for Pdgfd blocking peptide
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (By similarity). May play an important role in control of lens epithelial cell proliferation. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
42,128 Da
NCBI Official Full Name
Platelet-derived growth factor D
NCBI Official Synonym Full Names
platelet derived growth factor D
NCBI Official Symbol
Pdgfd
NCBI Official Synonym Symbols
Scdgfb; rSCDGF-B
NCBI Protein Information
platelet-derived growth factor D
UniProt Protein Name
Platelet-derived growth factor D
Protein Family
UniProt Gene Name
Pdgfd
UniProt Synonym Gene Names
Iegf; Scdgfb; PDGF-D; SCDGF-B; PDGFD latent form; PDGFD receptor-binding form
UniProt Entry Name
PDGFD_RAT
NCBI Description
a growth factor with mitogenic activity in the central nervous system [RGD, Feb 2006]
Uniprot Description
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (). May play an important role in control of lens epithelial cell proliferation. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.
Research Articles on Pdgfd
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Product Notes
The Pdgfd pdgfd (Catalog #AAA9225995) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SCDGFB, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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