FAM109A blocking peptide

FAM109A Antibody (N-term) Blocking peptide

• Gene Names: FAM109A; SES1; IPIP27A
• Synonyms: FAM109A; FAM109A Antibody (N-term) Blocking peptide; Sesquipedalian-1; Ses1; 27 kDa inositol polyphosphate phosphatase-interacting protein A; IPIP27A; FAM109A blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 249

• Cellular Location: Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin- coated vesicle. Note: Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for FAM109A blocking peptide

Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.

NCBI and Uniprot Product Information

• NCBI GI #: 74728832
• NCBI GeneID: 144717
• UniProt Accession #: Q8N4B1; Q6PJL9; Q96MH8; J3KP50
• Molecular Weight: 28,364 Da
• NCBI Official Full Name: Sesquipedalian-1
• NCBI Official Synonym Full Names: family with sequence similarity 109 member A
• NCBI Official Symbol: FAM109A
• NCBI Official Synonym Symbols: SES1; IPIP27A
• NCBI Protein Information: sesquipedalian-1
• UniProt Protein Name: Sesquipedalian-1
• Protein Family: Sesquipedalian
• UniProt Gene Name: FAM109A
• UniProt Synonym Gene Names: Ses1; IPIP27A
• UniProt Entry Name: SESQ1_HUMAN

NCBI Description

This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

FAM109A: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane. Belongs to the sesquipedalian family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 12q24.12

Cellular Component: clathrin-coated vesicle; early endosome; recycling endosome; trans-Golgi network

Molecular Function: protein binding; protein homodimerization activity

Biological Process: endosome organization and biogenesis; receptor recycling; retrograde transport, endosome to Golgi