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Western Blot (WB) (Anti-PBRM1 Antibody at 1:1000 dilution + HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 193 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Mouse anti-Human PBRM1 Monoclonal Antibody | anti-PBRM1 antibody

PBRM1 Antibody

Gene Names
PBRM1; PB1; BAF180
Reactivity
Human
Applications
Western Blot
Synonyms
PBRM1; Monoclonal Antibody; PBRM1 Antibody; Purified Mouse Monoclonal Antibody (Mab); Protein polybromo-1; hPB1; BRG1-associated factor 180; BAF180; Polybromo-1D; PB1; anti-PBRM1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Sequence Length
1582
Applicable Applications for anti-PBRM1 antibody
Western Blot (WB)
Application Notes
WB~~1:1000
Antigen Type
Recombinant Protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Anti-PBRM1 Antibody at 1:1000 dilution + HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 193 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-PBRM1 Antibody at 1:1000 dilution + HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 193 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB)

(Anti-PBRM1 Antibody at 1:500 dilution + HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 193 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-PBRM1 Antibody at 1:500 dilution + HT-1080 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 193 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-PBRM1 antibody
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.
Product Categories/Family for anti-PBRM1 antibody
References
Xue Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:13015-13020(2000). Horikawa I.,et al.DNA Seq. 13:211-215(2002). Sekine I.,et al.Oncogene 24:2735-2738(2005). Ota T.,et al.Nat. Genet. 36:40-45(2004). Lemon B.,et al.Nature 414:924-928(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
184,043 Da
NCBI Official Full Name
protein polybromo-1
NCBI Official Synonym Full Names
polybromo 1
NCBI Official Symbol
PBRM1
NCBI Official Synonym Symbols
PB1; BAF180
NCBI Protein Information
protein polybromo-1
UniProt Protein Name
Protein polybromo-1
Protein Family
UniProt Gene Name
PBRM1
UniProt Synonym Gene Names
BAF180; PB1; hPB1; BAF180
UniProt Entry Name
PB1_HUMAN

NCBI Description

This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]

Uniprot Description

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Acts as a negative regulator of cell proliferation.

Research Articles on PBRM1

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Product Notes

The PBRM1 pbrm1 (Catalog #AAA9216860) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PBRM1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PBRM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the PBRM1 pbrm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PBRM1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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