Rabbit anti-Human WDR3 Polyclonal Antibody | anti-WDR3 antibody
WDR3 Antibody (N-term)
Western Blot (WB)
(WDR3 Antibody (N-term) western blot analysis in Hela,K562 cell line lysates (35ug/lane).This demonstrates the WDR3 antibody detected the WDR3 protein (arrow).)
Flow Cytometry (FC/FACS)
(WDR3 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
repeats. WD repeats are approximately 30- to 40-amino acid domains
containing several conserved residues, which usually include a
trp-asp at the C-terminal end. Proteins belonging to the WD repeat
family are involved in a variety of cellular processes, including
cell cycle progression, signal transduction, apoptosis, and gene
regulation.
McMahon, M., et al. J. Biol. Chem. 285(24):18309-18318(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Uniprot Description
WDR3: an ubiquitous nuclear WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.
Protein type: Unknown function; Nucleolus
Chromosomal Location of Human Ortholog: 1p12
Cellular Component: small subunit processome; nuclear membrane; nucleolus; nucleus
Molecular Function: snoRNA binding
Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Research Articles on WDR3
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Product Notes
The WDR3 wdr3 (Catalog #AAA9213291) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 208-236. The WDR3 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's WDR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the WDR3 wdr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WDR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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