Rabbit anti-Human WDR3 Polyclonal Antibody | anti-WDR3 antibody

WDR3, NT (WDR3, WD repeat-containing protein 3)

Cat. Num. AAA643184

• Gene Names: WDR3; DIP2; UTP12
• Reactivity: Human
• Applications: ELISA, Western Blot, Flow Cytometry, Functional Assay
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: WDR3; Polyclonal Antibody; NT (WDR3; WD repeat-containing protein 3); Anti -WDR3; anti-WDR3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-WDR3 antibody: ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)
• Application Notes: Suitable for use in Western Blot, Flow Cytometry, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500; Flow Cytometry: 1:10-50
• Immunogen: WDR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the N-terminal region of human WDR3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(WDR3 Antibody (N-term) western blot analysis in Hela,K562 cell line lysates (35ug/lane).This demonstrates the WDR3 antibody detected the WDR3 protein (arrow).)

Flow Cytometry (FC/FACS)

(WDR3 Antibody (N-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-WDR3 antibody

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.

Product Categories/Family for anti-WDR3 antibody

Antibodies; Abs to WD Repeat Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 5803221
• NCBI GeneID: 10885
• NCBI Accession #: NP_006775.1
• NCBI GenBank Nucleotide #: NM_006784.2
• UniProt Accession #: Q9UNX4
• Molecular Weight: 106,099 Da
• NCBI Official Full Name: WD repeat-containing protein 3
• NCBI Official Synonym Full Names: WD repeat domain 3
• NCBI Official Symbol: WDR3
• NCBI Official Synonym Symbols: DIP2; UTP12
• NCBI Protein Information: WD repeat-containing protein 3; dJ776P7.2 (WD repeat domain 3)
• UniProt Protein Name: WD repeat-containing protein 3
• Protein Family: WD repeat-containing protein
• UniProt Gene Name: WDR3
• UniProt Entry Name: WDR3_HUMAN

NCBI Description

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

Uniprot Description

WDR3: an ubiquitous nuclear WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Protein type: Unknown function; Nucleolus

Chromosomal Location of Human Ortholog: 1p12

Cellular Component: small subunit processome; nuclear membrane; nucleolus; nucleus

Molecular Function: snoRNA binding

Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)