Western Blot (WB)
(FBXL19 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the FBXL19 Antibody detected the FBXL19 protein (arrow).)
Rabbit anti-Human, mouse FBXL19 Polyclonal Antibody | anti-FBXL19 antibody
FBXL19 Antibody (C-term)
Gene Names
FBXL19; Fbl19; CXXC11; JHDM1C
Reactivity
Human, mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
FBXL19; Polyclonal Antibody; FBXL19 Antibody (C-term); F-box/LRR-repeat protein 19; F-box and leucine-rich repeat protein 19; FBL19; anti-FBXL19 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This FBXL19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-570 amino acids from the C-terminal region of human FBXL19.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.39 (varies by lot)
Sequence Positions
543-570
Sequence Length
665
Applicable Applications for anti-FBXL19 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(FBXL19 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the FBXL19 Antibody detected the FBXL19 protein (arrow).)
Western Blot (WB)
(FBXL19 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the FBXL19 Antibody detected the FBXL19 protein (arrow).)
Related Product Information for anti-FBXL19 antibody
Members of the F-box protein family, such as FBXL19, are
characterized by an approximately 40-amino acid F-box motif. SCF
complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM
603134), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F box, and they
interact with ubiquitination targets through other protein
interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied
by OMIM].
characterized by an approximately 40-amino acid F-box motif. SCF
complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM
603134), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F box, and they
interact with ubiquitination targets through other protein
interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied
by OMIM].
Product Categories/Family for anti-FBXL19 antibody
References
Martin, J., et al. Nature 432(7020):988-994(2004)
Katoh, M., et al. Int. J. Mol. Med. 14(6):1109-1114(2004)
Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Katoh, M., et al. Int. J. Mol. Med. 14(6):1109-1114(2004)
Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75707
NCBI Official Full Name
F-box/LRR-repeat protein 19 isoform 1
NCBI Official Synonym Full Names
F-box and leucine-rich repeat protein 19
NCBI Official Symbol
FBXL19
NCBI Official Synonym Symbols
Fbl19; CXXC11; JHDM1C
NCBI Protein Information
F-box/LRR-repeat protein 19
UniProt Protein Name
F-box/LRR-repeat protein 19
Protein Family
UniProt Gene Name
FBXL19
UniProt Synonym Gene Names
FBL19
UniProt Entry Name
FXL19_HUMAN
NCBI Description
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Description
FBXL19: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: SCF ubiquitin ligase complex
Molecular Function: DNA binding; zinc ion binding
Biological Process: proteasomal ubiquitin-dependent protein catabolic process
Research Articles on FBXL19
Similar Products
Product Notes
The FBXL19 fbxl19 (Catalog #AAA9201354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 543-570. The FBXL19 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's FBXL19 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the FBXL19 fbxl19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBXL19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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