Structure
(Structure of C1050|Canavalia ensiformis; O-Guanidino-L-homoserine; L-a-Amino-g-[guanidinooxy]-n-butyric acid)
L-Canavanine Sulfate Biochemical
L-Canavanine Sulfate
Purity
Molecular Biology Grade~98% (TLC)
Synonyms
L-Canavanine Sulfate; L-Canavanine Sulfate biochemical
Purity/Purification
Molecular Biology Grade
~98% (TLC)
~98% (TLC)
Form/Format
White, crystalline powder
CAS Number
2219-31-0
Molecular Formula
C5H12N4O3 • H2SO4
Elemental Analysis
Carbon, Nitrogen: As reported
Preparation and Storage
Lyophilized powder may be stored at 4 degree C.
Structure
(Structure of C1050|Canavalia ensiformis; O-Guanidino-L-homoserine; L-a-Amino-g-[guanidinooxy]-n-butyric acid)
Structure
(Structure of C1050|Canavalia ensiformis; O-Guanidino-L-homoserine; L-a-Amino-g-[guanidinooxy]-n-butyric acid)
Related Product Information for L-Canavanine Sulfate biochemical
Canavanine, nitric oxide synthase inhibitor, is an analog of arginine. Both are imported into the cell via the same high-affinity permease, which is encoded by the can1 locus. High-level resistance to canavanine occurs exclusively because of mutation at this locus, but low-level resistance can arise at a number of other loci.
Because canavinine is a competitive inhibitor, arginine must be excluded from media used for testing sensitivity to the drug. Canavanine resistance must also be scored under high-nitrogen conditions, such as those provided by SD or SC medium, since the CAN1 permease will then provide the only entry route to the cell for arginine and canavanine. In the presence of low-nitrogen conditions, effectively those provided by YPD medium, the general amino acid permease (GAP) system is induced and arginine and canavanine can also be taken up by this route. In addition, Can r Arg-auxotrophs are viable on YPD but are inviable on synthetic media because they are unable to take up arginine.
Because canavinine is a competitive inhibitor, arginine must be excluded from media used for testing sensitivity to the drug. Canavanine resistance must also be scored under high-nitrogen conditions, such as those provided by SD or SC medium, since the CAN1 permease will then provide the only entry route to the cell for arginine and canavanine. In the presence of low-nitrogen conditions, effectively those provided by YPD medium, the general amino acid permease (GAP) system is induced and arginine and canavanine can also be taken up by this route. In addition, Can r Arg-auxotrophs are viable on YPD but are inviable on synthetic media because they are unable to take up arginine.
Product Categories/Family for L-Canavanine Sulfate biochemical
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Product Notes
The L-Canavanine Sulfate (Catalog #AAA6066097) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "L-Canavanine Sulfate, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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