anti-Human, Mouse Collagen IV alpha2 Antibody | anti-CO4A2 antibody
Collagen IV alpha2 Antibody
Gene Names
COL4A2; ICH; POREN2
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Immunogen affinity purified
Synonyms
Collagen IV alpha2; Collagen IV alpha2 Antibody; Collagen alpha-2(IV) chain; alpha 2 type IV collagen; canstatin; collagen type IV alpha 2; anti-CO4A2 antibody
Reactivity
Human, Mouse
Specificity
Collagen IV alpha2 Antibody detects endogenous levels of total Collagen IV alpha2
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
1712
Applicable Applications for anti-CO4A2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:100-1:500
IHC: 1:50-1:200
IF: 1:100-1:500
Immunogen
A synthesized peptide derived from human Collagen IV alpha2
Preparation and Storage
Store at-20 degree C for 1 year
Related Product Information for anti-CO4A2 antibody
Heterogeneous nuclear ribonuclearproteins (hnRNPs) are nucleic acid binding proteins and have critical roles in DNA repair, telomere regulation, and transcriptional gene regulation. hnRNP G has tumor suppressive activity and this RNA binding protein which may be involved in pre-mRNA splicing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42 kDa
NCBI Official Full Name
collagen alpha-2(IV) chain preproprotein
NCBI Official Synonym Full Names
collagen type IV alpha 2 chain
NCBI Official Symbol
COL4A2
NCBI Official Synonym Symbols
ICH; POREN2
NCBI Protein Information
collagen alpha-2(IV) chain
UniProt Protein Name
Collagen alpha-2(IV) chain
UniProt Gene Name
COL4A2
NCBI Description
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. The C-terminal portion of the protein, known as canstatin, is an inhibitor of angiogenesis and tumor growth. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008]
Uniprot Description
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Research Articles on CO4A2
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Product Notes
The CO4A2 col4a2 (Catalog #AAA8511895) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Collagen IV alpha2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Collagen IV alpha2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:100-1:500. Researchers should empirically determine the suitability of the CO4A2 col4a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Collagen IV alpha2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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