Western Blot (WB)
(MOSC2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOSC2 antibody detected the MOSC2 protein (arrow).)
Rabbit MOSC2 Polyclonal Antibody | anti-MOSC2 antibody
MOSC2 Antibody (C-term)
Gene Names
MARC2; MOSC2
Reactivity
Mouse (Predicted Reactivity: Monkey, Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MOSC2; Polyclonal Antibody; MOSC2 Antibody (C-term); Mitochondrial amidoxime reducing component 2; mARC2; 1---; Molybdenum cofactor sulfurase C-terminal domain-containing protein 2; MOSC domain-containing protein 2; Moco sulfurase C-terminal domain-containing protein 2; MARC2; anti-MOSC2 antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Monkey, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the C-terminal region of human MOSC2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
304-333
Sequence Length
335
Applicable Applications for anti-MOSC2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(MOSC2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOSC2 antibody detected the MOSC2 protein (arrow).)
Western Blot (WB)
(MOSC2 Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOSC2 antibody detected the MOSC2 protein (arrow).)
Related Product Information for anti-MOSC2 antibody
Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.
Product Categories/Family for anti-MOSC2 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Aberg, K., et al. Biol. Psychiatry 67(3):279-282(2010)
Havemeyer, A., et al. J. Biol. Chem. 281(46):34796-34802(2006)
Anantharaman, V., et al. FEMS Microbiol. Lett. 207(1):55-61(2002)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Aberg, K., et al. Biol. Psychiatry 67(3):279-282(2010)
Havemeyer, A., et al. J. Biol. Chem. 281(46):34796-34802(2006)
Anantharaman, V., et al. FEMS Microbiol. Lett. 207(1):55-61(2002)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38023
NCBI Official Full Name
mitochondrial amidoxime reducing component 2
NCBI Official Synonym Full Names
mitochondrial amidoxime reducing component 2
NCBI Official Symbol
MARC2
NCBI Official Synonym Symbols
MOSC2
NCBI Protein Information
mitochondrial amidoxime reducing component 2
UniProt Protein Name
Mitochondrial amidoxime reducing component 2
UniProt Gene Name
MARC2
UniProt Synonym Gene Names
MOSC2; mARC2; MOSC domain-containing protein 2; Moco sulfurase C-terminal domain-containing protein 2
UniProt Entry Name
MARC2_HUMAN
Uniprot Description
MOSC2: As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 1.-.-.-; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: 1q41
Cellular Component: mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; peroxisome
Molecular Function: nitrate reductase activity; molybdopterin cofactor binding; molybdenum ion binding; pyridoxal phosphate binding
Biological Process: detoxification of nitrogen compound; nitrate metabolic process
Research Articles on MOSC2
Similar Products
Product Notes
The MOSC2 marc2 (Catalog #AAA9205752) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 304-333. The MOSC2 Antibody (C-term) reacts with Mouse (Predicted Reactivity: Monkey, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's MOSC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MOSC2 marc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOSC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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