Testing Data
(Western blot with KC Polyclonal AntibodyLane 1: 80 ug Jurkat cell lysateLane 2: 80 ug 3T3 cell lysateBlocking/Dilution buffer: 5% NFOM (1 hr at RT) / TBST Lox-1 Polyclonal Antibody used at 1:1000 dilution - O/N at 4 degree C.Goat Anti-Rabbit IgG peroxidase conjugated used at 1:10,000 dilution - 1 hr at RT.Predicted band size: -7.8 kDa.Observed band size: -7.8 kDa. )
Rabbit KC Polyclonal Antibody | anti-KC antibody
KC Antibody
Shipping: Ships on cold packs.
Testing Data
(Western blot with KC Polyclonal AntibodyLane 1: 80 ug Jurkat cell lysateLane 2: 80 ug 3T3 cell lysateBlocking/Dilution buffer: 5% NFOM (1 hr at RT) / TBST Lox-1 Polyclonal Antibody used at 1:1000 dilution - O/N at 4 degree C.Goat Anti-Rabbit IgG peroxidase conjugated used at 1:10,000 dilution - 1 hr at RT.Predicted band size: -7.8 kDa.Observed band size: -7.8 kDa. )
Testing Data
(Western blot with KC Polyclonal AntibodyLane 1: 80 ug Jurkat cell lysateLane 2: 80 ug 3T3 cell lysateBlocking/Dilution buffer: 5% NFOM (1 hr at RT) / TBST Lox-1 Polyclonal Antibody used at 1:1000 dilution - O/N at 4 degree C.Goat Anti-Rabbit IgG peroxidase conjugated used at 1:10,000 dilution - 1 hr at RT.Predicted band size: -7.8 kDa.Observed band size: -7.8 kDa. )
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]
Uniprot Description
CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; cell; extracellular region; cytosol
Molecular Function: growth factor activity; chemokine activity; CXCR chemokine receptor binding; cytokine activity
Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of superoxide release; response to molecule of bacterial origin; positive regulation of potassium ion transport; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; inflammatory response; acute inflammatory response; regulation of cell proliferation
Research Articles on KC
Similar Products
Product Notes
The KC cxcl1 (Catalog #AAA840366) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KC Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting (0.5-4 ug/ml) and Immunohistochemistry (5 ug/ml). However, the optimal concentrations should be determined individually. Blocking peptide is available separately. Researchers should empirically determine the suitability of the KC cxcl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
