Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant TAL1 protein (red) or empty vector (blue) stained using TAL1 antibody)

Mouse TAL1 Monoclonal Antibody | anti-TAL1 antibody

TAL1 antibody

Gene Names
TAL1; SCL; TCL5; tal-1; bHLHa17
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
TAL1 antibody was purified by affinity chromatography.
Synonyms
TAL1; Monoclonal Antibody; TAL1 antibody; Monoclonal TAL1; Anti-TAL1; T-cell acute lymphocytic leukemia 1; SCL; bHLHa17; TCL5; Class A basic helix-loop-helix protein 17; Stem cell protein; T-cell leukemia/lymphoma protein 5; BHLHA17; TAL 1; TAL-1; anti-TAL1 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4A6
Purity/Purification
TAL1 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
331
Applicable Applications for anti-TAL1 antibody
Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes
FC: 1:100
WB: 1:2000
Biological Significance
Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.
Cross-Reactivity
Human
Immunogen
TAL1 antibody was raised in mouse using a full length recombinant protein of human TAL1 (NP_003180) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Flow Cytometry (FC/FACS)

(Flow Cytometric analysis of HEK293T cells transfected with either recombinant TAL1 protein (red) or empty vector (blue) stained using TAL1 antibody)

Flow Cytometry (FC/FACS) (Flow Cytometric analysis of HEK293T cells transfected with either recombinant TAL1 protein (red) or empty vector (blue) stained using TAL1 antibody)

Western Blot (WB)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TAL1 protein (Right) or empty vector (Left) detected with TAL1 antibody)

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant TAL1 protein (Right) or empty vector (Left) detected with TAL1 antibody)
Related Product Information for anti-TAL1 antibody
Mouse monoclonal TAL1 antibody
Product Categories/Family for anti-TAL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,548 Da
NCBI Official Full Name
T-cell acute lymphocytic leukemia protein 1 isoform 1
NCBI Official Synonym Full Names
T-cell acute lymphocytic leukemia 1
NCBI Official Symbol
TAL1
NCBI Official Synonym Symbols
SCL; TCL5; tal-1; bHLHa17
NCBI Protein Information
T-cell acute lymphocytic leukemia protein 1
UniProt Protein Name
T-cell acute lymphocytic leukemia protein 1
Protein Family
UniProt Gene Name
TAL1
UniProt Synonym Gene Names
BHLHA17; SCL; TCL5; TAL-1; bHLHa17
UniProt Entry Name
TAL1_HUMAN

Uniprot Description

TAL1: a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Protein type: Transcription factor; DNA-binding; Oncoprotein

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: transcription factor complex; histone deacetylase complex; nuclear chromatin; nucleus

Molecular Function: protein binding; enzyme binding; protein heterodimerization activity; histone deacetylase binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; erythrocyte maturation; cell fate commitment; positive regulation of chromatin assembly or disassembly; megakaryocyte differentiation; embryonic hemopoiesis; positive regulation of transcription, DNA-dependent; astrocyte fate commitment; positive regulation of erythrocyte differentiation; locomotory behavior; negative regulation of transcription from RNA polymerase II promoter; positive regulation of mitotic cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; positive regulation of protein complex assembly; positive regulation of cell division; erythrocyte differentiation; spinal cord association neuron differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; platelet formation; angiogenesis; basophil differentiation

Disease: Leukemia, Acute Lymphoblastic

Research Articles on TAL1

Similar Products

Product Notes

The TAL1 tal1 (Catalog #AAA833366) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TAL1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB). FC: 1:100 WB: 1:2000. Researchers should empirically determine the suitability of the TAL1 tal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.