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SDS-Page

HAI-1 Active Protein | SPINT1 active protein

HAI-1 Protein, Mouse, Recombinant (hFc Tag)

Gene Names
Spint1; HAI-1
Purity
>95% as determined by SDS-PAGE
Synonyms
HAI-1; HAI-1 Protein; Mouse; Recombinant (hFc Tag); Mouse HAI-1/SPINT1 Protein (Fc Tag); Hai1 Protein; serine peptidase inhibitor; Kunitz type 1; SPINT1 active protein
Ordering
For Research Use Only!
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Glu443
Species
Mouse
Activity
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-Arg-Pro-Lys-Pro-Val-Glu-NVAL-Trp-Arg-Lys(DNP)-NH2. The IC50 value is <1.5nM.
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Glu 30
Tag
C-human IgG1-Fc
Protein Construction
A DNA sequence encoding the mouse Spint1 (NP_058603.2)(Met1-Glu443) was expressed with the Fc region of human IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.

SDS-Page

SDS-Page
Product Categories/Family for SPINT1 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56,591 Da
NCBI Official Full Name
kunitz-type protease inhibitor 1
NCBI Official Synonym Full Names
serine protease inhibitor, Kunitz type 1
NCBI Official Symbol
Spint1
NCBI Official Synonym Symbols
HAI-1
NCBI Protein Information
kunitz-type protease inhibitor 1
UniProt Protein Name
Kunitz-type protease inhibitor 1
UniProt Gene Name
Spint1
UniProt Synonym Gene Names
Hai1; HAI-1
UniProt Entry Name
SPIT1_MOUSE

Uniprot Description

SPINT1: Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: embryonic placenta development; extracellular matrix organization and biogenesis; neural tube closure; positive regulation of glial cell differentiation

Research Articles on SPINT1

Similar Products

Product Notes

The SPINT1 spint1 (Catalog #AAA8122723) is an Active Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Glu44 3. It is sometimes possible for the material contained within the vial of "HAI-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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