Rabbit anti-Mouse SerpinB8 Monoclonal Antibody | anti-SerpinB8 antibody
Recombinant Anti-SerpinB8 Antibody, Rabbit Monoclonal
Gene Names
Serpinb8; CAP2; NK10; Spi8; CAP-2; ovalbumin
Reactivity
Mouse
Applications
ELISA
Purity
Protein A
Synonyms
SerpinB8; Monoclonal Antibody; Recombinant Anti-SerpinB8 Antibody; Rabbit Monoclonal; SerpinB8 Antibody; Rabbit MAb; serpin peptidase inhibitor; clade B (ovalbumin); member 8; Anti-CAP-2 Antibody; Anti-CAP2 Antibody; Anti-NK10 Antibody; Anti-ovalbumin Antibody; Anti-Spi8 Antibody; anti-SerpinB8 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
013
Specificity
Mouse SerpinB8
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SerpinB8 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Antibody Type
Recombinant Antibody
Immunogen
Recombinant Mouse SerpinB8 protein
Conjugation
Unconjugated
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SerpinB8 (rM SerpinB8).
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-SerpinB8 antibody
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.
Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.
Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.
References
Sumi, Y. et al., 1989, J. Biochem. 106: 703-7. Rawlings, N.D. et al., 2004, Biochem J. 378: 705-16. Gillard, A. et al., 2006, Am J Nephrol. 26 (1): 34-42. Filleur, S. et al., 2009, J Cell Biochem. 106 (5): 769-75. de Koning, P.J. et al., 2009, Pancreas. 38 (4): 461-7.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,150 Da
NCBI Official Full Name
serpin B8 isoform 1
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade B, member 8
NCBI Official Symbol
Serpinb8
NCBI Official Synonym Symbols
CAP2; NK10; Spi8; CAP-2; ovalbumin
NCBI Protein Information
serpin B8; serine protease inhibitor 8; serine (or cysteine) peptdiase inhibitor, clade B, member 8; serine (or cysteine) proteinase inhibitor, clade B, member 8
UniProt Protein Name
Serpin B8
Protein Family
UniProt Gene Name
Serpinb8
UniProt Entry Name
SPB8_MOUSE
Uniprot Description
SERPINB8: Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing
Protein type: Inhibitor
Cellular Component: extracellular space; cytoplasm; cytosol
Molecular Function: serine-type endopeptidase inhibitor activity; protease inhibitor activity
Biological Process: negative regulation of peptidase activity
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Product Notes
The SerpinB8 serpinb8 (Catalog #AAA8111217) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Anti-SerpinB8 Antibody, Rabbit Monoclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SerpinB8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000. Researchers should empirically determine the suitability of the SerpinB8 serpinb8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SerpinB8, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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