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SDS-PAGE

Serpinb8 recombinant protein

Recombinant Mouse SerpinB8 Protein (His tag)

Gene Names
Serpinb8; CAP2; NK10; Spi8; CAP-2; ovalbumin
Purity
> 94 % as determined by SDS-PAGE
Synonyms
SerpinB8; Recombinant Mouse SerpinB8 Protein (His tag); Serpinb8; CAP-2; CAP2; NK10; Spi8; ovalbumin; Serpinb8 recombinant protein
Ordering
For Research Use Only!
Host
Baculovirus-Insect Cells
Purity/Purification
> 94 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0
Sequence Length
374
Application Notes
The recombinant mouse SERPINB8 consists of 385 amino acids and has a calculated molecular mass of 43.6 kDa as estimated in SDS-PAGE under reducing conditions.
Predicted N Terminal
Ala 24
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for Serpinb8 recombinant protein
Background: Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.

Description: A DNA sequence encoding the mouse SERPINB8 (NP_035589.1) (Met 1-Pro 374) was expressed, with a C-terminal polyhistidine tag.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,150 Da
NCBI Official Full Name
serpin B8 isoform 1
NCBI Official Synonym Full Names
serine (or cysteine) peptidase inhibitor, clade B, member 8
NCBI Official Symbol
Serpinb8
NCBI Official Synonym Symbols
CAP2; NK10; Spi8; CAP-2; ovalbumin
NCBI Protein Information
serpin B8
UniProt Protein Name
Serpin B8
Protein Family
UniProt Gene Name
Serpinb8

Uniprot Description

SERPINB8: Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 1|1 E2.1

Cellular Component: cytoplasm; cytosol; extracellular space

Molecular Function: serine-type endopeptidase inhibitor activity

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Product Notes

The Serpinb8 serpinb8 (Catalog #AAA2547097) is a Recombinant Protein produced from Baculovirus-Insect Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse SERPINB8 consists of 385 amino acids and has a calculated molecular mass of 43.6 kDa as estimated in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the Serpinb8 serpinb8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SerpinB8, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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