Immunohistochemistry (IHC)
(Immunochemical staining of human C3orf52 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human C3orf52 Polyclonal Antibody | anti-C3orf52 antibody
Anti-C3orf52 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
C3orf52; Polyclonal Antibody; Anti-C3orf52 Antibody; Rabbit Polyclonal; C3orf52 Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-TTMP Antibody; anti-C3orf52 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human C3orf52
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-C3orf52 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human C3orf52 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human C3orf52 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human C3orf52 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human C3orf52 in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-C3orf52 antibody
C3ORF52 (also called TTMP), located on chromosome 3q13.2, has a central transmembrane domain predicted to span the endoplasmic reticulum membrane. C3ORF52 gene contains 6 exons and span approximately 33 kb. C3ORF52 shares 68% amino acid identity with the mouse homolog. 3 alternatively spliced human isoforms have been reported. TPA-induced transmembrane protein (TTMP) is up-regulated following treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA) in the pancreatic cancer cell line HPAF-II. The up-regulation by TPA is triggered at the promoter level. Loss-of-function variants in C3ORF52 result in localized autosomal recessive hypotrichosis.
References
Malki L, et al. (2020) Loss-of-function variants in c3orf52 result in localized autosomal recessive hypotrichosis. Genet Med 22 (7): 1227-1234.
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Product Notes
The C3orf52 (Catalog #AAA8108310) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-C3orf52 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's C3orf52 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the C3orf52 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C3orf52, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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