Immunohistochemistry (IHC)
(Immunochemical staining of human OTOA in human spleen with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human OTOA Polyclonal Antibody | anti-OTOA antibody
Anti-OTOA Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
OTOA; Polyclonal Antibody; Anti-OTOA Antibody; Rabbit Polyclonal; OTOA Antibody; Rabbit PAb; Antigen Affinity Purified; Anti-CT108 Antibody; anti-OTOA antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human OTOA
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-OTOA antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:200-1:1000
Immunogen
E Coli-derived Human OTOA fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human OTOA fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human OTOA in human spleen with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human OTOA in human spleen with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-OTOA antibody
The OTOA gene (Locus: DNFB22) was first reported as one of the responsible genes for non-syndromic autosomal recessive hearing loss. OTOA is located on chromosome 16p12.2, and encodes otoancorin, a protein required for limbal attachment of the tectorial membrane, which is important for conditioning proper stimulation of the inner hair cells. Mutations in OTOA gene cause nonsyndromic hearing loss (DFNB22). Most alterations of OTOA associated with deafness have been detected in North African or Middle Eastern nationals, including Palestinians, Pakistanis, Qataris, Turkish, and Algerians.
References
Sugiyama K, et al. (2019) Mid-frequency hearing loss is characteristic clinical feature of otoa-associated hearing loss. Genes (Basel) 10 (9): 715.
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Product Notes
The OTOA (Catalog #AAA8110238) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-OTOA Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OTOA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:200-1:1000. Researchers should empirically determine the suitability of the OTOA for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OTOA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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