Immunohistochemistry (IHC)
(Immunochemical staining of human STAMBP in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human STAMBP Polyclonal Antibody | anti-STAMBP antibody
Anti-STAMBP Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
STAMBP; Polyclonal Antibody; Anti-STAMBP Antibody; Rabbit Polyclonal; STAMBP Antibody; Rabbit PAb; Antigen Affinity Purified; STAM binding protein; Anti-AMSH Antibody; Anti-MICCAP Antibody; anti-STAMBP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human STAMBP
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-STAMBP antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human STAMBP fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human STAMBP fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human STAMBP in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human STAMBP in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human STAMBP in human prostate with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human STAMBP in human prostate with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-STAMBP antibody
STAMBP (STAM Binding Protein) is a Protein Coding gene. The STAMBP gene, located on 2p13.1, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. STAMBP is a JAMM-family deubiquitinating enzyme containing the microtubule-interacting/transport domain and STAM-binding domain. STAMBP is widely expressed in the thyroid, brain, and other tissues. Microcephaly-capillary malformation syndrome is a congenital and neurodevelopmental disorder caused by biallelic mutations in the STAMBP gene. Among its related pathways are the EGF/EGFR Signaling Pathway and Metabolism of proteins.
References
Wu F, et al. (2019) Early-onset epilepsy and microcephaly-capillary malformation syndrome caused by a novel stambp mutation in a chinese boy. Mol Med Rep 20 (6): 5145-5151.Iwakami Y, et al. (2018) Stam-binding protein regulates melanoma metastasis through slug stabilization. Biochem Biophys Res Commun 507 (1-4): 484-488.Hori I, et al. (2018) A novel homozygous missense mutation in the sh3-binding motif of stambp causing microcephaly-capillary malformation syndrome. J Hum Genet 63 (9): 957-963.
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Product Notes
The STAMBP (Catalog #AAA8108199) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-STAMBP Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STAMBP can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the STAMBP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAMBP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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