Mouse anti-Human Tetranectin Monoclonal Antibody | anti-CLEC3B antibody

Anti-Tetranectin Antibody, Mouse Monoclonal

Cat. Num. AAA8106597

• Reactivity: Human
• Applications: ELISA
• Purity: Protein A
• Synonyms: Tetranectin; Monoclonal Antibody; Anti-Tetranectin Antibody; Mouse Monoclonal; Tetranectin/CLEC3B Antibody; Mouse MAb; C-type lectin domain family 3; member B; Anti-CLEC3B Antibody; Anti-TN Antibody; Anti-TNA Antibody; anti-CLEC3B antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Clone Number: 09
• Specificity: Human Tetranectin/CLEC3B
• Purity/Purification: Protein A
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-CLEC3B antibody: ELISA (EIA) (Det)
• Application Notes: ELISA (Det): This antibody will detect Human Tetranectin/CLEC3B in ELISA pair set.; In a sandwich ELISA, it can be used as detection antibody when paired with.
• Immunogen: Recombinant Human Tetranectin/CLEC3B Protein
• Conjugation: Unconjugated
• Preparation: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Tetranectin/CLEC3B (rh Tetranectin/CLEC3B). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Related Product Information for anti-CLEC3B antibody

Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize.

References

Iba K, et al. (2001) Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity. Mol Cell Biol. 21(22): 7817-25.Stoevring B, et al. (2006) Tetranectin in cerebrospinal fluid of patients with multiple sclerosis. Scand J Clin Lab Invest. 66(7): 577-83.Brunner A, et al. (2007) Expression and prognostic significance of Tetranectin in invasive and non-invasive bladder cancer. Virchows Arch. 450(6): 659-64.Iba K, et al. (2009) Impaired cutaneous wound healing in mice lacking tetranectin. Wound Repair Regen. 17(1): 108-12.Arellano-Garcia ME, et al. (2010) Identification of tetranectin as a potential biomarker for metastatic oral cancer. Int J Mol Sci. 11(9): 3106-21.Wang L, et al. (2010) Tetranectin is a potential biomarker in cerebrospinal fluid and serum of patients with epilepsy. Clin Chim Acta. 411(7-8): 581-3.

NCBI and Uniprot Product Information

• NCBI GI #: 60834603
• NCBI Official Full Name: tetranectin, partial
• Protein Family: Tetranectin