Rabbit anti-Human FCRL1 Polyclonal Antibody | anti-FCRL1 antibody
Anti-FCRL1 Antibody, Rabbit Polyclonal
Gene Names
FCRL1; FCRH1; IFGP1; IRTA5; CD307a
Reactivity
Human
Applications
ELISA
Purity
Protein A & Antigen Affinity
Synonyms
FCRL1; Polyclonal Antibody; Anti-FCRL1 Antibody; Rabbit Polyclonal; FCRL1/FCRH1 Antibody; Rabbit PAb; Antigen Affinity Purified; Fc receptor-like 1; Anti-CD307a Antibody; Anti-FCRH1 Antibody; Anti-IFGP1 Antibody; Anti-IRTA5 Antibody; anti-FCRL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human FCRL1/FCRH1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-FCRL1 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5000-1:10,000
Immunogen
Recombinant Human FCRL1/FCRH1 Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human FCRL1/FCRH1 (rh FCRL1/FCRH1). FCRL1/FCRH1 specific IgG was purified by Human FCRL1/FCRH1 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-FCRL1 antibody
Fc receptor-like protein 1, also known as FcR-like protein 1, Fc receptor homolog 1, IFGP family protein 1, Immune receptor translocation-associated protein 5 and FCRL1, is a single-pass type I membrane protein which contains threeIg-like C2-type (immunoglobulin-like) domains. It is a cell-surface membrane protein belonging to FCRL family and is preferentially expressed on B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It is detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. FCRL1 is specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level). Human Fc receptor-like molecules (FCRL1, FCRL2, FCRL3, FCRL4, FCRL5) have tyrosine-based immunoregulatory potential and are expressed by B-lineage subpopulations. FCRL1 may function as an activating coreceptor in B cells. It may also function in B cells activation and differentiation.
Product Categories/Family for anti-FCRL1 antibody
References
Du X. et al., 2008, Blood. 111 (1): 338-43. Kazemi T. et al., 2008, Int J Cancer. 123 (9): 2113-9. Baranov K. et al., 2008, J Immunol Methods. 332 (1-2): 73-81.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,068 Da
NCBI Official Full Name
Fc receptor-like protein 1 isoform 1
NCBI Official Synonym Full Names
Fc receptor like 1
NCBI Official Symbol
FCRL1
NCBI Official Synonym Symbols
FCRH1; IFGP1; IRTA5; CD307a
NCBI Protein Information
Fc receptor-like protein 1
Protein Family
NCBI Description
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Research Articles on FCRL1
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Product Notes
The FCRL1 (Catalog #AAA8105399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FCRL1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FCRL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5000-1:10,000. Researchers should empirically determine the suitability of the FCRL1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FCRL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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