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Fc Receptor-Like Protein 1 Recombinant Protein | FCRL1 recombinant protein
Recombinant Human Fc Receptor-Like Protein 1
Gene Names
FCRL1; FCRH1; IFGP1; IRTA5; CD307a
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Fc Receptor-Like Protein 1; Recombinant Human Fc Receptor-Like Protein 1; FcR-Like Protein 1; FcRL1; Fc Receptor Homolog 1; FcRH1; IFGP Family Protein 1; hIFGP1; Immune Receptor Translocation-Associated Protein 5; CD307a; FCRL1; FCRH1; IFGP1; IRTA5; FCRL1 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
Sequence Length
366
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fragment
Ala17-Asn303
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
SDS-Page
SDS-Page
Related Product Information for FCRL1 recombinant protein
Protein Construction: Recombinant Human Fc Receptor-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala17-Asn303 is expressed with a 6His tag at the C-terminus.
Background: Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.
Background: Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular Mass: 32.2kDa
Actual Protein Molecular Mass: 39-50kDa
Actual Protein Molecular Mass: 39-50kDa
NCBI Official Full Name
Fc receptor-like protein 1 isoform 2
NCBI Official Synonym Full Names
Fc receptor like 1
NCBI Official Symbol
FCRL1
NCBI Official Synonym Symbols
FCRH1; IFGP1; IRTA5; CD307a
NCBI Protein Information
Fc receptor-like protein 1
UniProt Protein Name
Fc receptor-like protein 1
Protein Family
UniProt Gene Name
FCRL1
UniProt Synonym Gene Names
FCRH1; IFGP1; IRTA5; FcR-like protein 1; FcRL1; FcRH1; hIFGP1
NCBI Description
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Uniprot Description
May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.
Research Articles on FCRL1
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Product Notes
The FCRL1 fcrl1 (Catalog #AAA2556666) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Fc Receptor-Like Protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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