Mouse VAChT Monoclonal Antibody | anti-SLC18A3 antibody
VAChT Antibody: FITC
Scientific Background: VAChT is a member of the vesicular amine transporter (VMAT) family. The encoded transmembrane protein transports acetylcholine into secretory vesicle for release into the extracellular space. Acetylcholine (Ach) transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene.
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]
Uniprot Description
SLC18A3: Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 10q11.2
Cellular Component: membrane; integral to plasma membrane; plasma membrane
Molecular Function: acetylcholine transmembrane transporter activity
Biological Process: synaptic transmission; acetylcholine transport; neurotransmitter secretion